Is Myelofibrosis (MF) the same as Myelodyplastic syndrome?

Posted by bmarkable @bmarkable, Jun 10 6:51am

Is Mylofibrosis the same as mylodisplastic syndrome?

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Hi @bmarkable. Myelofibrosis (MF) and Myelodyplastic syndrome are two different blood conditons.

Myelofibrosis (MF) is disorder in which abnormal blood cells and fibers build up in the bone marrow. Myelofibrosis is part of a group of diseases called myeloproliferative disorders/neoplasms (MPN), and are characterized for abnormal cells which sometimes harbor mutations in the JAK pathway. The symptoms associated with primary myelofibrosis differ and are associated to a build of abnormal blood cells and fibers in the bone marrow.
If I remember correctly I believe you were diagnosed with MF.
https://www.healthline.com/health/myelofibrosis
For comparison, Myelodysplastic Syndrome (MDS) is a term for a group of frequent malignant stem cell diseases. People with MDS have low numbers of red blood cells (anemia), and the cells may have a mutation in their DNA. It can progress to a more serious form of Acute Myeloid Leukemia (AML) so patients with MDS are closely monitored for any changes. The risk factors/staging can be determined with genetic testing.
https://www.verywellhealth.com/what-are-myelodysplastic-syndromes-mds-2252548
How are you doing with your MF?

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