My TRIMIX experience

Posted by maverick75 @maverick75, Jan 4, 2025

I've been using Trimix for about six months with outstanding results. It did take some experimentation to figure out the best way to make it work for me. With hopes that it may help others, here's what I discovered using this medication: (BTW, I'm 71, one year post SBRT and 4 months Orgovyx)
- I have had to use the oral antidote several times (works well) in the early dose experimentation days for super hard erections lasting more than three hours (4tablets of 30 mg pseudoephedrine. Don't make the mistake of buying the extended release pseudoephedrine tabs). Make sure you have this on hand before you start this medication!
- I had to find the sweet spot for the injection site and depth. For me turns out to be the 10 and 2 o'clock position with the 1/2" needle almost fully inserted around mid-shaft.
- Shelf life on the Trimix in the refrigerator is limited. I can definitely see a difference in the results at the 3-4 week period. For me, it became pretty useless after 4 weeks, even at a higher dose. To help extend the life, I now fill all syringes with the needed dose as soon as I get the medication and immediately place all syringes into the freezer until needed. Now, I take a syringe out about 30 min before needed and it's ready to go. This is working well and my pharmacist said this should extend the shelf-life to 6 months or more.
- After injecting, massage the entire penis and base to help distribute the medication throughout the muscle structure. This will help significantly.
- Stand for the first 5-10 minutes after injection as gravity aids in the blood flow into the penis.
This medication has been a lifesaver for me. I was afraid I'd never see a useful erection again. Now, I'm back to 18 in that regard-- actually better than 18 as my erection stays hard even after an orgasm! Best of luck guys! Be aware that your partner may hide your medication if you use it to often. (-:

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Congratulations. A quick question: After you organsm, and have remained erect for another hour or two, and...if your wife.girlfriend is up for another round, have you been able to climax a second or third time? When we had a prostate, seminal vesicles, and vas deferens, we would climax, and that was usually it...you went flaccid and were "unable" for a while until you recovered and could go again...perhaps longer than "keeping her in the mood" allowed. If we are not ejaculating, but remain hard, and achieve climax purely through the frenulum stimulation on the underside of our penis, then that "should" - in my mind - be unlimited. Anyone have something to offer?

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Has anyone tried Trimix gel?

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Profile picture for rlpostrp @rlpostrp

Congratulations. A quick question: After you organsm, and have remained erect for another hour or two, and...if your wife.girlfriend is up for another round, have you been able to climax a second or third time? When we had a prostate, seminal vesicles, and vas deferens, we would climax, and that was usually it...you went flaccid and were "unable" for a while until you recovered and could go again...perhaps longer than "keeping her in the mood" allowed. If we are not ejaculating, but remain hard, and achieve climax purely through the frenulum stimulation on the underside of our penis, then that "should" - in my mind - be unlimited. Anyone have something to offer?

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@rlpostrp no answer. Everyone is fifferent

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"Yep"...everyone is different. Even with my dedicated career as the Director of Clinical and Anatomical Laboratory Services ("The Lab"), not being a physician, I never knew the vast array of cellular pathology that can exist within the one diagnosis of prostate cancer. And of course, a lot has to do with "when" it was diagnosed. Five men with the same "acinar adenocarcinoma" (most typical variety), may be diagnosed when they are just a Gleason 3+3=6, 3+4=7, 4+4=8, 4+5=9, 5+4=9, etc. Along with what their Decipher Score reveals and the flat-out microscopic revelation as to the aggressiveness of "their" particular cancer, they all have different journeys and outcomes. That is the only real value to a Gleason Score: It tells you "at the time of diagnosis" that you "have" cancer, and for likely "how long"...that it was only an early 3+3=6, on up to a late 5+4=9, and anything in between.
I often think of "Dilbert" cartoonist Scott Adams who just passed away from prostate cancer at age 68. "Why?" Did he wait too long to get his annual PSA and then it was too late? Did he get his PSA and like MANY men, go into fear and denial mode, doing nothing about it until it was too late (bone pain from metastasis, etc.)? Or was he diagnosed with a particularly high Decipher Score ("bad genes"), and with a particularly aggressive case for which there was no hope? It drives me crazy. As that Director of Lab, I was well aware of the fact that there are four main types of leukemia, and a total of 8 with subtypes. They almost always appear the same microscopically, and "behave" and respond the same way to treatment. You don't really see as many weird variations within the type of leukemia the patient has. That is not true with prostate cancer, women's breast cancer, and some other cancers. So you are so very correct: we're all different...our prostate cancers, while having lots in common, are still very different.

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As a person who has to pay out of pocket for Trimix I am wondering what is everyone paying on average for it? I know there is different strengths; but I am just trying to get a general idea. Thanks.

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@necrons
When I was using it I was paying $400 for 10 injections.
Jake

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