My Experience with Evenity

I’m just on Medicare part A/B with supplement Cigna

I also go to infusion site, so maybe that is the difference for the cost.

I am about to receive my sixth dosage and have not experienced any substantial side effects. Soreness at the injection sites for about a day; that is all. My Medicare with Plan B covers all and I receive my shots in my endocrinologist’s office. I am anticipating moving to Reclast after I complete my 12 dosages.

Good day to all..
... my first day as a member and trying to learn very fast from your comments and sequences. I am a caretaker and together with the patient (Pnt) will decide in the next week if it will be Reclast or Prolia, after two years of Tymlos ....which yielded a bit of progress from -2.8 to -2.6. The names of the meds you all mention (Evenity, Fosomax, etc) are unknown to us... were they taken before Reclast or Prolia? Also, reading some of your comments and others I read this morning on this site, there have been extreme results from practically no effects of the infusions to ER prolonged stays. I have learned some today but the results I read about haven't helped given the broad range of results. There has been some pressure to select Reclast over Prolia, although the side effects at the first Reclast infusion can be hard, it seems. I apologize for the way I structure sentences. English is not my first language.. Would appreciate any specific comments with side effects from Reclast initial and along the process.. thank you

Prior to being put on Evenity, I had I believe 3-4 Reclast infusions. I had no side effects.

Hi Renee: thank you for the info... I am a caretaker suddenly deeply involved in the decision making for the patient. We are in the process of fast learning about Reclast and other meds whose names come up on the subject. Need to make a decision before the 28th about taking Reclast or Prolia or letting Osteoporosis following its course (almost unthinkable). Can Evenity be administered pre, along or post Reclast? I know this is a dr's issue but no there meds have been mentioned at all. So far it is Reclast or Prolia or ........

Hi. This is a post I created to share some resources that were particularly helpful to me when I was navigating treatment decisions. It includes links to a couple of videos that describe medication options and medication sequencing. I found them to be incredibly helpful starting points in learning about the medication options.
https://connect.mayoclinic.org/discussion/new-osteoporosis-diagnosis-where-to-start/

has anyone been on evenity after tymlos

Hi and welcome @front. That's quite a complicated situation you're in. I'm so glad you've managed to come here!

There are basically three classes of medications for osteoporosis.
Antiresorptives: Reclast, Fosamax, Actonel
Monoclonal antibodies: Evenity, Prolia
Anabolics: Tymlos and Forteo

Evenity is often prescribed prior to Reclast. Simply put, it builds bone as do Tymlos and Forteo. Reclast and Prolia maintain bone.

Doctors wildly vary regarding the best medication sequence. If the patient is deemed to have had a good response to medication that builds bone (as measured primarily by DEXA and TBS) , the doctor will then often prescribe a drug that is designed to maintains bone. If the patient's results are less than ideal after the bone-building medication, doctors will often continue a bone-building medication treatment and re-evaluate after a year.

In regards to Reclast vs Prolia, my personal opinion (mostly based on what I've read here) is that Reclast is a better choice. Prolia can cause fractures once stopped, and according to many doctors it must be continued for life or switched to a different medication. It's a more complicated scenario imho. Prolia also seems to have a higher potential for causing necrosis of the jaw than Reclast.
For reference, I started with Fosamax, then did one year of Evenity followed by one year of Tymlos and I had my first Reclast infusion May 2025. I had zero side effects whatsoever from Reclast. Some people do, and there's just no way to know if that will happen.
Evenity can not be taken along with Reclast. It can be done before Reclast and after, although that sequence is unusual.

As far as letting osteoporosis run its course, that's a judgment call. Much depends on the patient's overall health and their wishes. These are very powerful drugs, and may cause serious side effects that severely impair quality of life. There are many other ways to improve osteoporosis which you can explore on this site. Several people have chosen to not use medications.

I hope this helps. If you have any more questions we can answer, please don't hesitate to ask.
Best wishes to you and warm regards.

I got my first reclast infusion and 13 days ago and I've had major problems ever since. I was very sick initially starting 12 hours after the infusion where I was throwing up for 24 hours, fairly high fever definite flu like symptoms with pain throughout my body including headache and just felt terrible. Since then I've been so tired and I have pain in my one side lower back my doctor calls it the pelvic area but I say lower back left side that won't go away. I also had swelling in my ankles. It has not been a good experience. I plan to make this the only time I use the reclast. I had been on prolia for 5 years and did very well no problems. Prior to that I had been on forteo which gave me hearing loss, mild but hearing loss so I could not take that anymore. Does anybody have any suggestions for me for the future. I am in a class that's called healthy bones so I try to work with bone strengthening exercises. I take something called algaecal calcium and some people can just do that and they're fine but it wasn't enough for me. You can take strontium with that and again that's supposed to strengthen bones. I did not get enough help from that. I may have to go that route in the future I'm not sure. If you can give me any advice I'd appreciate it and any advice on what to do now for this pain that's not going away and the tiredness. Thank you. Jayne