Multiparametric MRI (mpMRI) over diagnosis?

Posted by handera @handera, Dec 2, 2023

Due to an accelerating PSA (5.06 to 7.8 in 7 months) a MPMRI (multiparametric MRI) was ordered that indicated 3 lesions (PIRADS 3, 4 and 5 - one each). Fusion biopsy targeted the three lesions and 12 additional random cores obtained (21 cores total). Results indicated two of the lesions were Gleason 3 + 3, but the random cores found 2 additional cores with small percentages of Gleason 3 + 4. My question is whether it is typical for an MRI not to find the more aggressive cancer? Could it be due to the fact that the MRI machine was a 1.5T and not the more advanced 3.0T type? Or was it simply a misread MRI????

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On my journey I have been diagnosed with BPH that has morphed into possible PC cancer because of the PSA test interpretation because I chose to pursue the REZUM treatment. As a result I struggle to manage my anxiety regarding PC..... I am resisting invasive procedures until I am convinced there is adequate risk/reward compared to watchful waiting. I am no longer pursuing REZUM and have re committed to meds and supplements which thankfully still work. I will be starting from scratch in January as I am seeing a new and different Urologist.

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Definitely recommend pet scan.Had one last month which showed spot on 6th rib.After medical oncologist group consultation they determined spot had been there on previous scans and biopsy not necessary

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