Does anyone else have MGUS?

I've been diagnosed with MGUS and also taking gabapentin. I'm finding I have extreme fatigue after about an hour of a dose. Would you please explain to me what your side effects were? I told my PCP that I thought it was the gaba that was causing my sleepiness and he said he had never heard of that. Thanks!

@maddie2023 I feel you. I did not like gabapentin either. I am taking 200mg daily of pregabalin now. No side effects but I’m not sure it’s doing much to change the narrative.
I keep moving. The pain that I get in my toes is sometimes pretty extreme. I just push through it and keep on keeping on. At 72, I think being able to do that is going to be a pretty good adaptive life strategy.
Water aerobics has helped a lot of my friends who are arthritic and although it’s kind of a pain because we don’t have a heated pool in my community, I think I’m going to drive to use the heated pool in a nearby community.
I’ve also been doing physical therapy due to a fall and that has helped me tremendously by strengthening my core. I guess Medicare has a lifetime cap on physical therapy and I am reaching that maximum. I think that’s ridiculous because physical therapy can assist in keeping people out of nursing homes and help them live more independently even with physical limitations. I have my last session tomorrow and after that I plan to replicate what I’ve learned in physical therapy at the senior citizen center and work out on their machines and with free weights
I hope you can find some relief. If you find something that gives you good results, please do post them.

Hi, I was dx. Oct. 24 with MGUS. As of last May my M spike was .08 & I had 1 lambda showing itself. I asked if we could delay the entire body bone X-rays and my Hematologist agreed unless my numbers changed significantly. (I didn’t want the xtra radiation ☢️ yet)
My next blood evaluation is Nov.
As with all of us with MGUS, it’s a waiting game. I was told at my age 68 that I would probably die of something else. Comforting huh?
I have a friend w/MM and she had gone thru terrible things but is still surviving after 12 yrs. My heart goes out to all suffering anything in relation to our diagnosis’s MGUS, SMM or MM. Bless all of us. Perseverance is our motto!

I was diagnosed jan2025.
IgM 15g/l
Flc kappa 6. It has risen to 7 in 6 months.
Is this signifcant ?

Yes I have MGUS; was diagnosed 23 years ago in 2002. It is truly a waiting game.
While my M spike and FLC lambda have gone up, they are reasonably stable. My previous Mayo hematologist (who retired) wanted bloods drawn every 3 months. My current hematologist is more relaxed about all of this and I have blood tests every six months now. After 23 years I do not get nervous anymore waiting for results,
I guess time will tell. I do not have symptoms that I know of.

@maddie2023 I feel you. I did not like gabapentin either. I am taking 200mg daily of pregabalin now. No side effects but I’m not sure it’s doing much to change the narrative.
I keep moving. The pain that I get in my toes is sometimes pretty extreme. I just push through it and keep on keeping on. At 72, I think being able to do that is going to be a pretty good adaptive life strategy.
Water aerobics has helped a lot of my friends who are arthritic and although it’s kind of a pain because we don’t have a heated pool in my community, I think I’m going to drive to use the heated pool in a nearby community.
I’ve also been doing physical therapy due to a fall and that has helped me tremendously by strengthening my core. I guess Medicare has a lifetime cap on physical therapy and I am reaching that maximum. I think that’s ridiculous because physical therapy can assist in keeping people out of nursing homes and help them live more independently even with physical limitations. I have my last session tomorrow and after that I plan to replicate what I’ve learned in physical therapy at the senior citizen center and work out on their machines and with free weights
I hope you can find some relief. If you find something that gives you good results, please do post them.

I've been told to just keep moving around and walking (which I started doing around my neighborhood). Purchased a good pair of NB sneakers which are pretty much cushioned and make it easier for me to walk in them. I find sitting still just aggravates things so I try to not sit around that much. Good luck to you in February. Who knows maybe someday they'll come up with some solution. Right now my Dr pushes the meds. No thank you, I don't like the feeling I got after taking gabapentin for 4 days. That was enough to convince me I had to find other remedies....