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Does anyone else have MGUS?
I was diagnosed with MGUS last October and although I've done a lot of research, I feel there's still so much I don't know. Does anyone else have MGUS?
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My.mother's agr is 65.She got M band 0.4 and free light Kappa 100.Our haemotologist told to have bone marrow biopsy and aspiration.Her aspiration reports have arrived.Can anyone please explain what are the results
Our haemotologist performed bone marrow aspiration and biopsy yesterday.The bone marrow aspiration i have attached hereby.Can you please explain if there is any abnormalities in this you see regarding MM
I have read that FLCs rise due to infection which makes sense since you had covid. Don’t understand about why lambda would stay elevated but not kappa.
Both kappa and lambda were elevated at my MGUS diagnosis over 3 years ago but now just the lambda remains high. Just within normal range ratio.
I see a MM doc who is monitoring me and thinks it’s nothing to worry about. The M spike isn’t detectable since initial level of 0.2 g/dl in 2021.
FLCs can be high if you have kidney disease but that’s normal for me. And connected to autoimmune diseases.
I think there’s a lot of research currently about FLCs and why they are elevated etc.
How were you and who diagnosed the chronic Lyme? I’ve been told I may have it, Lyme tests showed some positive tests but my RA DR AND PCP won’t “diagnose” bc they don’t treat it. Found out I have MGUS recently - don’t know what to do with that one either - except yearly tests. I’m interested in getting Lyme diagnosed to see what can be done bc maybe it’ll help with all I have.
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1 ReactionHello,
I've noticed that my urine sometimes is a smidge more bubbly than normal, and sometimes it looks like there's lots of ... little stuff ... floating in it. Not fine enough to call it cloudy but not large either. Has anyone else had this issue? I'm worried about excess protein. My latest round of tests have my FLC amounts and ratio within normal levels but M-Spike popped up slightly to 1.3 from 1.2 six months prior. Currently on an annual testing cycle but the urine has me concerned. No other symptoms, luckily.
Just curious if this is something I should contact my doc about. Thx.
@nboulet
When you reference “685,” to what value does this refer?
Have you spoken to your hematologist about what values would necessitate further study?
Your entry was most interesting to me.
I have IgG lambda MGUS.
My free light chains (both kappa and lambda) escalated to very high levels when I was exposed to COVID by our cleaning people. I was asymptomatic but clearly had a case of Covid.
My kappa went to normal within a couple of months but the lambda stayed high.
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2 ReactionsI might add that I have also had MGUS for more than 20 years. I was diagnosed in 2002 with an “abnormal paraprotein.” I suspect that I had this earlier.
While my numbers have risen over the years and I have some “risky” features like a father with SMM, I still am not in a class of either SMM or MM.
Also a website called SparkCures may have some clinical trials of interest.
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3 ReactionsWhat number increased to 685? We are not doctors but maybe we can refer you to helpful websites and information.
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1 ReactionI have had MGUS for 20 years, I was diagnosed at the age of around 45 years old, the value numbers were so low. I was told not to worry about it, in the last two years, the MGUS blood test value numbers, 2022 Christmas time 173 and then November 2024 the value numbers increased 400% to 685. I am waiting to get to see a hematologist. Not sure what these value numbers are all about. Also, I have been living with progressive neuropathy. that has got worse in the last two years, no balance hard to walk as I am now 65 years old.
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