Does anyone else have MGUS?

@karishmagupta There are many of us here who understand the concern and stress you might be feeling, waiting to see the doctor on Friday 1/3/2025!

Because we are not medical professionals, we shouldn't nor can we interpret test results. Your medical team looks at several different results and puts them together to understand what your mother is experiencing.

I hope you will let us know what you find out on Friday. Meanwhile, please rest easy.
Ginger

She will be getting her appointment till Friday 3rd January.I got this aspiration report from lab today only but the biopsy report will be coming on Friday ..i am not able get the meaning of these ones .So was a bit worried .I asked here with the hope that if someone gives me some clarity and I can have a bit peaceful sleep at night ..It's ok I can understand here the consultation is more important

@karishmagupta, going through the diagnostic process is hard, especially the waiting. It sounds like you have received the results of your mother's bone marrow biopsy before meeting her medical team to discuss the results and next steps. Fellow patients can't interpret these results for you on a forum like this one.

Biopsy results are only one piece of the puzzle in the diagnostic process. Your mother's medical team is the only one who can interpret the results along with her medical history, other studies and clinical exam.

I know you are worried. When does your mom have an appointment to review the results and next steps with her doctor?

When is your next appointment?

Thank you. My hematologist was the one that diagnosed me with MGUS. No one seems to want to touch the idea of me having chronic Lyme - I’ve asked RA doctors, infectious disease, pcp, hematology, etc. what symptoms do you have with MGUS? My WBC count was so low for a couple of years that finally a new RA doc sent me to the hematologist. Said to re do bloodwork in a year. So for now I’m just trucking along with all the others issues that could all fall under Lyme.

Definitely see a hematologist/oncologist re MGUS. Local primary may not take it as seriously, and it is interesting that all Myeloma cases are preceded by MGUS, but not all MGUS converts to Multiple Myeloma. About 1% convert or so I have read. So have it checked at least every year if not 6 months. Better safe than sorry. I did see one trial in the literature that is ongoing that is treating MGUS in the country so stay tuned with that. Recommend keeping up with the literature as the cancer breakthroughs change so rapidly it seems to me. NCI has some good literature but if u have a local medical library that is good.

I also take the most conservative approach, however at the cancer hospital in my area I opted for the test. The M spike and diagnosis is not a known factor. According to the literature this is an uncommon cancer and my hematologist wanted to know exactly where we were when I went to him. It will allow them to intervene at an appropriate time if they have good benchmarks to start with. In my case the M spike has been in my blood since 2019. I read stories where people never convert, some convert in 5- 7 years etc. Best to take the recommendation of the cancer specialist. Ask for conscious sedation and you won't even fell it. No side effects and gives your oncologist valuable information to treat you specifically.

I have MGUS since 2019. However no one noticed in my blood work until 2024. I suggest u go to a cancer specialist/hematologist if not already. The story from my primary is "oh I have many patients with MGUS" Nothing to worry about. Even from my local cancer center. So I traveled to the Cancer hospital to get a second opinion. And the non cancer MD's stress you do not have cancer. Well I know that but isn't cancer best caught by early diagnosis. My cancer specialist has a very calming but serious recognition of MGUS. so get a second opinion from a Hematologist/oncologist and then decide. I'll stick with the cancer specialist. Occasional check in with the locals if I cant get to the distance if I need for the hematologist oncologist.

Sorry..I have cropped the details .kindly please reply to the image now Iattached hereby.Are there chances of MM?

Hello @karishmagupta, you may notice I removed the image from your post. I did so because it had personal identifying information. Mayo Clinic Connect is a public website and we want to protect our members' identities and personal information.

If you'd like to share images or reports, we recommend blurring out or removing any information that can identify you before posting an image.

My.mother's agr is 65.She got M band 0.4 and free light Kappa 100.Our haemotologist told to have bone marrow biopsy and aspiration.Her aspiration reports have arrived.Can anyone please explain what are the results