Does anyone else have MGUS?

@leslie2121 - you said, "But for a few susceptible individuals [the mRNA vaccine] may have triggered autoimmune disorders, kidney inflammation and/or nephrotic syndrome and plasma cell dycrasias. There are a few studies just now being released online that the public can access that suggest this."

Do you have the link(s) to those studies? TIA.

Patty:
You are kind to always respond, and I recognize I could be more focused on gratitude and the positive direction things seem to be going.
Part of my persistence in researching this is hoping to be as healthy as possible for as long as I can.
I think the turmeric/curcumin supplements may be helping, and I wouldn’t have known about trying that if I hadn’t done my own research.
I also wonder ( and this is controversial!) what role the mRNA vaccine had in this. I believe in the benefits of vaccines- I even spent a few weeks volunteering to give shots for the County Medical Association during the pandemic, partly to get mine a little early. ( was an RN for my first career) I don’t think anyone was conspiring, and it ended the worst of the pandemic thankfully!

But for a few susceptible individuals it may have triggered autoimmune disorders, kidney inflammation and/or nephrotic syndrome and plasma cell dycrasias.
There are a few studies just now being released online that the public can access that suggest this. I also have a family history of autoimmune disease as well as myself.

I don’t understand what “small peaks in several lanes” means. My doctor drew the SPEP for normal, and for MGUS. It’s a distinct sharp spike that indicates a monoclonal gammopathy. I don’t have that - just several little bumps in gamma area.. He was frankly baffled and said the only way to know is to do another BMB and it wasn’t warranted.

I’ve had significant fatigue, dizziness, and frankly some depression the past 2 years which has been slowly resolving. Trying to look forward now.

I appreciate this supportive group very much and wish you the best! 🥹

A lot more(250) lambda, 20%in bone marrow and the checkup is next week so will find out more then!
Mascot

Ginger:
I wasn’t wanting more frequent appointments and was actually thrilled with the positive direction the labs are taking.
And I do plan to keep seeing the specialist- though he said he could direct a pcp in what exactly to look for, but I don’t have a super great pcp so will keep seeing the MM doc.

Anyway- I am baffled why things got better! I have had a pretty healthy diet, and exercise regularly with long walks up hills, gardening & housework. I’ve added some supplements?
Maybe stress related?

@leslie2121 I personally wouldn't look at the result of one set of labs as a concern. Look at the trend. You mentioned you will go back in 6 months. If there is any reason you don't feel comfortable with that, ask to be seen at three months.

And, as Patty @pmm mentioned, stick with your hematologist/oncologist, please. They are better educated and better equipped to address concerns that may arise, and "catch" a change.

Good to hear that fatigue, dizziness, depression seems to be lifting for you. There can be many small reasons for these symptoms, that come together and can create a larger presence. What can you think of that has helped you get over these hurdles? Diet change? More/different exercises? Mindful work to address the issues? Just curious, and it might help others!
Ginger

Patty:
You are kind to always respond, and I recognize I could be more focused on gratitude and the positive direction things seem to be going.
Part of my persistence in researching this is hoping to be as healthy as possible for as long as I can.
I think the turmeric/curcumin supplements may be helping, and I wouldn’t have known about trying that if I hadn’t done my own research.
I also wonder ( and this is controversial!) what role the mRNA vaccine had in this. I believe in the benefits of vaccines- I even spent a few weeks volunteering to give shots for the County Medical Association during the pandemic, partly to get mine a little early. ( was an RN for my first career) I don’t think anyone was conspiring, and it ended the worst of the pandemic thankfully!

But for a few susceptible individuals it may have triggered autoimmune disorders, kidney inflammation and/or nephrotic syndrome and plasma cell dycrasias.
There are a few studies just now being released online that the public can access that suggest this. I also have a family history of autoimmune disease as well as myself.

I don’t understand what “small peaks in several lanes” means. My doctor drew the SPEP for normal, and for MGUS. It’s a distinct sharp spike that indicates a monoclonal gammopathy. I don’t have that - just several little bumps in gamma area.. He was frankly baffled and said the only way to know is to do another BMB and it wasn’t warranted.

I’ve had significant fatigue, dizziness, and frankly some depression the past 2 years which has been slowly resolving. Trying to look forward now.

I appreciate this supportive group very much and wish you the best! 🥹

@leslie2121
Oh I’m glad to hear you found a good LCSW match. This is Social Work month. Another reason to celebrate.
Stress can be crippling. For me, it makes me feel physically weak and even nauseous. Getting a handle on that is no small feat.

Good question!
If from an outside source then my own body may recover with time and rest.
2. Intentional stress reduction allowed my immune system to respond.
3. Curcumin? But I think it was already getting better.

As far as the depression (and anxiety), I did seek out an excellent LCSW with the oncology team. Yay to therapy! The psychiatrist didn’t recommend meds as it was an adjustment disorder. But I wonder…