Lupron: Anyone have muscle weakness and severe leg pain?

TRY theraworx from Walgeens generic Rub it on muscles

Been on Lupron since April 2023 and had leg pains. Upon speaking to a pharmacist who had worked in oncology he recommended taking an antihistamine like 24 hour Allegra or Claritin. Since taking Allegra I've had very few leg cramps. A few 1 to 2 a week much milder ones occur in the first ten days after the injection. He told me they studied leg cramps and found those patients taking 24 hour antihistamines rarely had leg cramps. Might want to give it a try. Good luck!

Hand pain. I was on Lupron and Erleada for 13 months and I have been off all meds now for 10 months. About a month ago I got pain in my right hand and fingers and I cannot now make a fist and the palm and back of that hand and fingers ache and burn and hurt. The pain is now starting in my left hand. Has anyone else had this sort of problem and if so can you give me a recommendation. Tylinol 8 hr and arthritis cream help, but I am looking for other treatment. Thanks

I identify with your leg pain. Gleason 9. Metastatic. I’ve done chemo and radiation, now on Lupron and Nubeqa. So weak I can hardly climb steps. Physical therapy helps. Several short walks or exercise bike rides per day seems to help.

Ditto for me. Lupron isn't easy

Lupron severely adversely effects your muscles. I have difficulty getting out of my chair and unstable in my walking. Gleason 9, CR, aggressive, locally advanced. I am told that it helps to keep me alive so I willingly accept the side effects. I was taken off all meds 10 months ago but I still feel side effects from Lupron and Erleada

I can surely understand. My daily 3 mile walk, which is fairly elevated is
much more difficult now than before hormone treatment. Hips down to
the feet. Ibuprofen helps slightly. Little feedback from the urologist, and
oncologist!

So, kam23, your latest post says that the Lupron wasn't the cause of the leg pain, right?
FYI for the thread: I've been on 3-month leuprolide/Lupron for a year, I think, and recently added abiraterone/prednisone. No pain, but I notice I can't climb as many stairs as I used to, or as easily the ones I still can -- perhaps unrelated to the ADT+, though.

I stopped Lupron in August of last year (2022).

My testosterone still has not returned to within range.

I have not dared walk to the store for the last year, for my muscle mass is too weak, and I am afraid of stepping up on curbs and stepping down from them.

I realize that age makes a big difference in the speed of recovery. . I am 86.

Good luck, God bless, I'm 69 here. Have a good weekend.