Luminal B?

Posted by lesliek808 @lesliek808, 2 days ago

Hi all:

I am ER+/PR-/HER2+. I had a mastectomy at age 59 (was not given a choice of lumpectomy because of spread over 1/2 of breast) without reconstruction on the right side in 2023. It grew very quickly since I get mammograms every year like clockwork. No sentinel lymph nodes involved. On exemestane now.

My oncologist never said "Luminal B" but after research, it seems that I have Luminal B cancer which is worst than Luminal A.

Can anyone share their journey with luminal B symptoms? It is classified as more aggressive so worried about recurrence elsewhere. Since I'm Her2+, was given a choice prior to mastectomy to start chemotherapy. Maybe I should have done that.

Thoughts on this?

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vegada | @vegada | 1 day ago

What test show whether you have Luminal A or B breast cancer?

prarysky | @prarysky | 1 day ago

As I recall, having a higher Ki-67 level which is determined from your tumor biopsy is one difference between Luminal A (lower Ki-67) and Luminal B (higher Ki-67). A higher Ki-67 can indicate a faster growing cancer. There may be other factors, such as grade of the tumor, which distinguish luminal A vs luminal B.