LDL-cholesterol and osteoporosis
I've started reading McCormick's book 'Great Bones'. He attributes his osteoporosis for the main part to too many MALPS, caused by a high LDL. He also says: "Couple this with a red blood cell count (RBC) below 4.0 million/mm3 and you probably have excessive MALP-production (see pages 46-47).
I searched and found e.g. this article from 2022: https://pmc.ncbi.nlm.nih.gov/articles/PMC8896571/ "High Low-Density Lipoprotein Cholesterol Levels are Associated with Osteoporosis Among Adults 20–59 Years of Age" .
That article links to this article from 2020: https://pubmed.ncbi.nlm.nih.gov/32163637/ "The Effect of Plasma Lipids and Lipid-Lowering Interventions on Bone Mineral Density: A Mendelian Randomization Study."
By the way, despite McCormick's expectations, according to my google research, tocotrienols don't look effective in lowering LDL cholesterol.
For me, discovering that high levels of LDL cholesterol can form a significant contribution to osteoporosis, is an eye opener.
Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.
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Me too. Thanks for this info.
Thanks so much !
Thanks for sharing this. I had no idea LDL levels were linked to osteoporosis.
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1 ReactionInteresting how cholesterol can impact osteoporosis. At a Medicare checkup almost two years ago, I asked my GP if there were any blood tests to look at things like inflammation in my body. She said she would order a LP(a) test. When the results came back in the high range, that led to referral to heart doctor who ordered a cardiac CT scan that showed some calcium buildup in my LAN. Although that was not a high number, I was also referred to a heart specialist in Lipidology. From there was put on an every other week injection of Repatha.
When learning more about my LP(a) being elevated, found that one in five people have elevated LP(a), but doctors don’t routinely test for it in the U.S. They DO test for it in Europe and Canada. Since this elevated number indicates that the liver does not process cholesterol normally, which results in high bad cholesterol. Since you are making the association between osteoporosis and cholesterol, I’m wondering if the medical community is not making associations appropriately. If you knew there was a test that would show if you have elevated LP(a) that one in five people have, would you ask for it? Disappointed that this test that would show elevated LP(a) is not offered to patients (it’s a once in a lifetime, non-changing number). The U.S. needs to get onboard with Canada and Europe in LP(a) testing.
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8 Reactions@reginacl
Yes!!!! We should be tested. I also believe that women should start getting dexa scans at 40. And men should also receive dexa scans.
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1 ReactionI was surprised to learn this recently as well and that it seems to have occurred while using foods from Mayo Clinic to control my cholesterol that has been helpful. I take calcium, Vitamin D3 and recently started MK4 to address osteoporosis concerns. Would appreciate any further information/guidance on this issue.
Thank you.
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1 Reaction@reginacl Actually, I'm in Europe and my former GP refused to test me on LP(A), as "we don't do that, because we already know everything we need to know". I might ask my current GP at my next appointment...
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1 Reaction@osteoprob48
Are you asking for osteoporosis feedback or the cholesterol?
The use of supplements to address osteoporosis and their effect on cholesterol.
Which supplements? Are you currently on Osteoporosis meds? What are your dexa scores?