Doctor is concerned about Kidney GFR numbers: Should I be?

hello,@ pamphilips1.
GFR lower than 60mL/min is an indication of kidney disease.
120mL/min is consider normal for a young person and it declines with age.
The speed of the reduction is interesting and your doctor is proactive on your behalf.
Supplements can greatly affect GFR rates, especially the B vitamins, vitamin D and minerals too.

Really? How does Vitamin B12 affect it? A lot? I’ve taken Vitamin D3 for many years and never saw a problem. Last eGFR was 96 and I have had type 1 diabetes for over 23 years. I’ve been on B12 treatment since May, so…..I’m concerned. Will get tests in November.

It seems to me that whatever is causing the low GFR involves a change made after the 112 reading.
Some synthetic B12 supplements contain cyanocobalamin or aluminum. Our kidneys don't process either very well so you could have a build up affecting your kidneys. High doses of B12 have been noted in association with faster decline of kidney function. Methylcobalamin is natural, but it is also more bioavailable, so you might be absorbing a higher dose.
You might change brands and/or lower the dose for October before the November draw.

Thank you for responding, I do not take B12. Does Semiglutide effect kidney function?

Hello

I wish these vitamins are causing the numbers to lower but I am not on
B vitamins or vitamin D.

I'm wishing too that it will turn out to be something reversible. Are there other recent dietary or medication changes. Still, you're in the normal range.

I take the shot semiglutide but have stopped taking the shots to see if that may be the cause.
No changes in medications.

Hello! I have actually joined this group for a very similar reason - to figure out if semaglutide injections are having a negative effect on my dads kidneys (his recent labs were a bit concerning to me but his NP is not concerned).
Frustrating, if there is a sudden decline even if it’s not major, we fail to treat it proactively and are too late most times.

Wondering if you had labs redrawn and if so, were there were any improvements since discontinuing the injection?

The B12 did impact my eGFR. I’m still normal, but it’s down and I’m furious. I have to figure this out. Man….do the injections go through your kidneys too? I’m holding off on oral route for right now. Think I’m going to speak with my endocrinologist. The neurologist is the one who prescribed the mega doses.