Keytruda + Lenvima For Recurrent Endometrial Serrous Carcinoma

Posted by beviebk1 @beviebk1, Oct 15 10:09am

I was diagnosed with stage 4 endometrial cancer in 2021. I had a total hysterectomy and my omentum was also removed. My initial CA-125 was 500, but after carboplatin-taxol chemo my number went down to 15. I had ct scans every 3 months and all were good until this year. Three lymph nodes showed some small increased sizes and after another 2 scans they had continued to increase. A biopsy confirmed that my serrous carcinoma had returned. I've had no symtpoms and feel fine. I'm now starting my treatment with Keytruda and Lenvima.
I'm looking to hear from others that have had this treatment and get some tips and encouragement.

Interested in more discussions like this? Go to the Gynecologic Cancers Support Group.

Colleen Young, Connect Director | @colleenyoung | Oct 23 3:25pm

Hi @beviebk1, I’m sorry to hear that cancer has made a return appearance. I’m tagging both @paula21 and @rainna who have experience with pembrolizumab (Keytruda) and lenvatinib (Lenvima) for endometrial cancer.

Bev, have you started this new treatment yet? How are you doing?

beviebk1 | @beviebk1 | Oct 27 11:44am

In reply to @colleenyoung "Hi @beviebk1, I’m sorry to hear that cancer has made a return appearance. I’m tagging both..." + (show)

Hi Colleen,
I've started my Keytruda about 2 weeks ago. I'm scheduled for my 2nd. infusion in a week.
I've been on the Lenvima at 4mg. for a week and will probably move up to 8mg. by the end of next week.
So far I've been doing well with no apparent side effects.
Thanks so much for responding. I look forward to more conversation and firsthand experiences from others.

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