Keytruda + Lenvima For Recurrent Endometrial Serrous Carcinoma
I was diagnosed with stage 4 endometrial cancer in 2021. I had a total hysterectomy and my omentum was also removed. My initial CA-125 was 500, but after carboplatin-taxol chemo my number went down to 15. I had ct scans every 3 months and all were good until this year. Three lymph nodes showed some small increased sizes and after another 2 scans they had continued to increase. A biopsy confirmed that my serrous carcinoma had returned. I've had no symtpoms and feel fine. I'm now starting my treatment with Keytruda and Lenvima.
I'm looking to hear from others that have had this treatment and get some tips and encouragement.
Interested in more discussions like this? Go to the Gynecologic Cancers Support Group.
Hi @beviebk1, I’m sorry to hear that cancer has made a return appearance. I’m tagging both @paula21 and @rainna who have experience with pembrolizumab (Keytruda) and lenvatinib (Lenvima) for endometrial cancer.
Bev, have you started this new treatment yet? How are you doing?
Hi Colleen,
I've started my Keytruda about 2 weeks ago. I'm scheduled for my 2nd. infusion in a week.
I've been on the Lenvima at 4mg. for a week and will probably move up to 8mg. by the end of next week.
So far I've been doing well with no apparent side effects.
Thanks so much for responding. I look forward to more conversation and firsthand experiences from others.
Hello all .My name is Bert I was diagnosed with stage four follicle thyroid cancer , I start my treatment Lenvatinib 14 mg today anyone used this much and did it appear to work ? Anyone respond will be Appreciate Thanks
I haven't started Lenvatinib (and am plotting how to avoid it), but I was discussing it with the nurse practitioner yesterday. She said that they start people at 20 mg, but that almost nobody stays that high. She said most people end up at 14 or 10 mg. Like most cancer drugs, it works pretty well for some people but not others.
Hi @bert60, welcome. I recommend that you post your question in the Thyroid Cancer support group here: https://connect.mayoclinic.org/group/thyroid-cancer/
Here's a discussion you may wish to join in the group:
- Anyone taking Lenvatinib?
https://connect.mayoclinic.org/discussion/anyone-taking-lenvatinib/