Anyone had IsoPSA testing?

Posted by smoore4 @smoore4, Nov 21, 2024

“I would never want to belong to any club that would have someone like me for a member.”
- Woody Allen*, Annie Hall

Seriously, I know I am going to count on this group for plenty of things, so thought I would introduce myself - Steve, hi.

I am early in the PCa process. One of the diagnostic tests I had done was an IsoPSA (8.0). I don't see much chatter about that here, and I am wondering if it is because it is new, or it is not accepted as a standard test. Any thoughts?

* originally Groucho Marx

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

@ialogic

My isoPSA is 47/psa 16. Biopsy mri negative

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😳 Mine was 13 and I thought it was through the roof.

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@detroitmike

I have had iso psa 23 doctor was surprise how high it was ,had mri came back pi rads 2 my follow up is on 4/22 no pain, minor urinary problems sleep through the night fine ,have been working out a lot and drink probably a gallon of water every day. Do have some urgency at times but not all the time.

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With that high an ISOPSA, you should be able to light up a PSMA PET scan because something is causing that number. Your result is high, IsoPSA >10 is associated with a sevenfold higher risk of csPCa (clinically significant prostate cancer).

You could do a PSMA Pet test before a biopsy just to see if there’s cancer somewhere else.

Would be interesting to see your actual PSA.

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@jeffmarc

With that high an ISOPSA, you should be able to light up a PSMA PET scan because something is causing that number. Your result is high, IsoPSA >10 is associated with a sevenfold higher risk of csPCa (clinically significant prostate cancer).

You could do a PSMA Pet test before a biopsy just to see if there’s cancer somewhere else.

Would be interesting to see your actual PSA.

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My isoPSA was 13 and my PSMA did not light up like a christmas tree. There was some visible uptake but the report noted that it was not “abnormal”.

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