Is anyone supplementing their calcium, k2 and vit d with an NMN supple

I started that regime a couple of years ago and, for no good reason, laid off the NMN. That said, I’ve had modest increases on my BDS.

I've never heard of it before but googled some research on it. Didn't too far but it's interesting it doesn't have more attention because the effects sound pretty good. Another natural source is cucumber and fortunately, I eat a lot of those 🙂 I wouldn't think this would interfere with the other vitamins you mention but don't really know.

@csrb7007 what is NMN ? Can it help stabilize OP ?

@nycmusic
https://www.healthline.com/health/nmn-nicotinamide-mononucleotide-benefits-side-effects-and-dosage

@csrb7007 thank you, very interesting….

I had not heard of this but I did find that there have not been any clinical trials in post menopausal women.

Direct clinical trial data specifically evaluating NMN's impact on bone mineral density (BMD) or bone turnover markers in postmenopausal women is currently limited.
While researchers have studied NMN extensively for general metabolic health, muscle performance, and safety in postmenopausal women (such as trials looking at NAD+ levels, insulin sensitivity, and lipid metabolism), direct human clinical endpoints measuring skeletal changes are still largely absent.
Instead, our current understanding comes from a combination of two distinct areas:
Preclinical and Animal Research: Studies using estrogen-deficient or ovariectomized mice (to mimic postmenopausal bone loss) have shown very encouraging results. They indicate that NMN can help mitigate bone loss by activating sirtuins (like SIRT1), supporting osteoblast function, and helping suppress excessive osteoclast-mediated bone breakdown.
General Human Trials: Human trials involving postmenopausal women have focused primarily on systemic and metabolic parameters. For instance, a notable trial conducted by Kyoto Doshisha University gave 300 mg of NMN daily to healthy postmenopausal women for 8 weeks and found it safely improved markers like DHEA-s, insulin sensitivity, and lipid profiles without adverse effects, but it did not track bone density or turnover markers.

Please don’t take calcium supplements unless you’ve had a blood test to look at your calcium levels. Extra calcium in your diet when it’s not needed will harden your arteries, add to plaque deposits, increase the opportunity for pseudo gout, and is just a bad idea. Gone are the days when calcium helps build strong bones when you’re a kid and older age it works against you. Talk to your doctor first and take a blood test before taking calcium supplements.