Interesting study about a new way to turn off inflammation

Posted by jeff97 @jeff97, Jan 20 5:12am

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@jeff97 This article was very interesting! Were you just “reading for pleasure” and found it or were you specifically looking for this article. If you find any follow-on articles, please post them! My AI disease is called ‘chronic inflammation…….”
Thank you!

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Profile picture for Becky, Volunteer Mentor @becsbuddy

@jeff97 This article was very interesting! Were you just “reading for pleasure” and found it or were you specifically looking for this article. If you find any follow-on articles, please post them! My AI disease is called ‘chronic inflammation…….”
Thank you!

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@becsbuddy
I use the Google news app to read news, and the article showed up there. I guess my Google search history caused that article to be included.

I will post any follow ups or other articles about new treatments. The treatment in this article sounds promising, since the medication has already been tested some on people, and it sounds like it takes effect immediately.

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Profile picture for Becky, Volunteer Mentor @becsbuddy

@jeff97 This article was very interesting! Were you just “reading for pleasure” and found it or were you specifically looking for this article. If you find any follow-on articles, please post them! My AI disease is called ‘chronic inflammation…….”
Thank you!

Jump to this post

@becsbuddy and @jeff97 If anyone wants to take a "deep dive" search "GSK2256294" at scholar.google.com.
Scientists have been studying it for a variety of issues for over 10 years.

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I’d jump at being part of those clinical trials. Can you imagine the stunning breakthrough if they found a cure to chronic inflammation diseases? It would instantly become a billion dollar industry. Big pharmaceutical would fight tooth and nail against one company having such power to take away their own billion dollar industries. The price of that drug would be unaffordable to the regular public in the USA.
It would be a miracle drug!

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Pure curcumin is already known to be an sEH blocker and curcumin has been known to be antiinflammatory for centuries.

I take nearly one gram of pure curcuminoids a day as part of my treatment for RA.

I am in full remission with perfect blood scores.

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Profile picture for rocksology @rocksology

I’d jump at being part of those clinical trials. Can you imagine the stunning breakthrough if they found a cure to chronic inflammation diseases? It would instantly become a billion dollar industry. Big pharmaceutical would fight tooth and nail against one company having such power to take away their own billion dollar industries. The price of that drug would be unaffordable to the regular public in the USA.
It would be a miracle drug!

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@rocksology Try searching for "clinical trials for GSK2256294" or "clinical trials for epoxy-oxylipins" I'm not sure if you will find anything, but worth a try.

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Profile picture for cptrayes @cptrayes

Pure curcumin is already known to be an sEH blocker and curcumin has been known to be antiinflammatory for centuries.

I take nearly one gram of pure curcuminoids a day as part of my treatment for RA.

I am in full remission with perfect blood scores.

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@cptrayes Wonderful " I am in full remission." Could you help me understand correctly.
Does that mean your inflammation scores went down as shown by blood tests or that your RA is in full remission.
Barbara

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Profile picture for blm1007blm1007 @blm1007blm1007

@cptrayes Wonderful " I am in full remission." Could you help me understand correctly.
Does that mean your inflammation scores went down as shown by blood tests or that your RA is in full remission.
Barbara

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@blm1007blm1007

Both.

My CRP is currently 2, and my ESR 6, down from 57 and 38 respectively.

When last measured my anti-CCP was borderline for RA , down from strongly indicating of RA, and has been heading downward so I haven't measured it again.

I have had one flare in on joint in 7 months and I could pin that to 3 sources of high cortisol levels that occurred at the same time.

Hope that helps!

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In the meantime, I am using Low Dose Naltrexone for inflammation control. It does require a slow titration process but my pain from inflammation is down about 50%.

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