Insulin Resistance and Fatty Liver

Posted by kinmeta @kinmeta, Jul 15, 2018

I am at the age of 56. For years I had fatty liver. I tried to improve the situation by physical exercise. Since July last year, every day I ran 3.5 mile on a running machine. Sadly, weight was not reduced and a recent ultrasound exam showed fatty liver worsened.
Further IGT test showed both glucose level and insulin level are moderately higher than normal. Doctor told me it is the case of insulin resistance associated with fatty liver.
I feel quite discouraged that I really tried my best but could not see any improvement.
Can anyone share the experience with me how to make things better with diet plus physical exercise?
Is my case serious enough to justify a medicine? Two widely used medicines in China are Metformin and TZDs. But, both have serious side effects, esp. Metformin hurts stomach and I already have serious stomach problems. Any other recommendations?
Or can anyone introduce me some medicine from natural materials, instead of from chemicals?
Thank you very much.

Liked by livermom

@user_ch2456688

how is fatty liver diagnosed? same question for insulin resistance?

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@mark_fugate, I definitely agree that we, the patients, must take responsibility of our health by being our own advocates. And that includes the research and the inclusion of conversation with our doctors along with the support of spouse and family. It is evident that both you and your wife are receiving the benefits of this effort. (My husband is eating healthier because of my nutritional needs, so we both benefit).
I want to thank you for the book reference, and the link that you have provided!
Rosemary

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@rosemarya

I would like to add this information to this discussion from Mayo Clinic about the Symptoms, Causes, Diagnosis, and Treatment.
https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567
Rosemary

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@contentandwell, I know what you mean about being an anomoly! We really ARE all different. and it amazes me how our doctors come even 'near' to figuring out our diseases!

I posted the Non-alcoholic Fatty Liver Disease as a reply to question that was posted earlier : "How is Fatty Liver disease diagnosed."

I don't know anything about the insulin resistance, though. After my transplant, I had to check my glucose levels and have insulin during the time when I was on a high dose of prednisone. But that is my only experience with it.
Hugs,
Rosemary

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@rosemarya

I would like to add this information to this discussion from Mayo Clinic about the Symptoms, Causes, Diagnosis, and Treatment.
https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567
Rosemary

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@rosemarya as I have mentioned, I too had bg problems when on a higher dose of prednisone.
These were most of my symptoms. The ascites I did not have until the very end. I, of course, had no idea but after I found out I had cirrhosis I discovered that all of these things that I was suffering from were known symptoms of cirrhosis.

* Declining platelet count
* Hand tremors
* Recently diagnosed diabetes
The above three things started more than 5 years before my cirrhosis diagnosis

* Terrible leg cramps. These started in my thighs at night and over time progressed to my lower legs and feet and sometimes hands
also. The thigh cramps were excruciating. These also started a couple of years before my diagnosis.
* Cold
* Trouble sleeping leading to day naps
* fluid retention in feet (edema)
* fluid retention in mid-section (ascites)
* Hand-writing deteriorating
* and, the big one — HE – irrational, tired
JK

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@rosemarya

I would like to add this information to this discussion from Mayo Clinic about the Symptoms, Causes, Diagnosis, and Treatment.
https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567
Rosemary

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@rosemarya Thanks for that great article, Rosemary. I never really understood how complex fatty liver disease was.

Teresa

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@dlewins

Metrormin has recognised *possible* side effects of a gastro-intestinal type. They are not everybody's experience and were not mine. Sadly some people make the assumption that side rejects are guaranteed when they certainly are not. Controlled release Metformin can often solve those gastric issues. Metformin can assist with reducing insulin resistance and research is showing that it can be protective against cardiac problems and some cancers. You might want to consider the "Newcastle Diet" to deal with both your fatty liver and weight – please see https://www.nhslothian.scot.nhs.uk/Services/A-Z/DiabetesService/PatientsCarers/Documents/SJH%20NEWCASTLE%20DIET%20BOOKLET2012.pdf This diet resulted from clinical research in the UK.

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Hi, @dlewins – just wanted to follow up with you and your mention of your experiences. Sounds like you've taken Metformin? Have you also experienced insulin resistance associated with fatty liver?

@mark_fugate and @musicflowers4u – wondering how you are doing?

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@dlewins

Metrormin has recognised *possible* side effects of a gastro-intestinal type. They are not everybody's experience and were not mine. Sadly some people make the assumption that side rejects are guaranteed when they certainly are not. Controlled release Metformin can often solve those gastric issues. Metformin can assist with reducing insulin resistance and research is showing that it can be protective against cardiac problems and some cancers. You might want to consider the "Newcastle Diet" to deal with both your fatty liver and weight – please see https://www.nhslothian.scot.nhs.uk/Services/A-Z/DiabetesService/PatientsCarers/Documents/SJH%20NEWCASTLE%20DIET%20BOOKLET2012.pdf This diet resulted from clinical research in the UK.

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I am doing well thank you for asking.

I had a short bout with fatty liver. The threat of a biopsy scared me onto the straight and narrow. My fatty liver threat was only for a very few months so I can not say whether it contributed to my insulin resistance.

I have take metformin for almost three years now and had Lantus and Humalog added this last May.

Liked by Lisa Lucier

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Is it aerobic exercise and getting your heart rate in the target zone?

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My mother and her mother both became insulin dependent Type 2 diabetics in their 60s. I am 66 and have been taking metformin for the last 10 years to "fight insulin resistance"; plain generic metformin worked for 6 months then started making me throwup every morning; two weeks later I was having diarrhea as well as throwing up; went on Glumetz for 3 years until my insurance would no longer cover it; took glucophage generic for 1 year and developed same gastrointestinal problems. Went back on Glumetz even though medicare won't cover it and after 9 months I have the same stomach and bowel issues. My bowels are so runny that I literally walk around with tp in my rear to prevent accidents in public. What else can I take for insulin resistance?

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