Immediate and severe Tymlos side effects.

Posted by anne905 @anne905, Aug 14 9:42am

Has anyone else experienced immediate and severe side effects from Tymlos, with their first injection?

I had a first and last injection of Tymlos in my doctors office a few weeks ago. I received the injection, and then became very dizzy with vertigo as the room seemed to tilt, and my heart rate elevated. I didn’t panic as that was somewhat to be expected. However, then steadily increasing pain started in my abdomen, spread to my lower spine, and extended up my spine into my head. The pain increased in intensity, bordering on intolerable. Then there was the onset of a tension headache like a vice grip on my brain, and tingling, burning in my limbs. I could only lie down and moan at that point. After about 20 - 25 minutes, the pain slowly began to recede.

A immediate determination was made that Tymlos is not for me, and I must go back to Prolia.

I was preparing for my 5th injection of Prolia, and had been experiencing increased muscular pain/ ache/ weakness with each previous injection; with only a nominal DEXA scan change.

This is why my doctor prescribed Tymlos instead to build bone first, before going back on Prolia in the future. I’ve not been able to tolerate any other drugs for Osteoporosis such as Fosamax.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

@apoind1

YES I have! I just started Tymlos 12/12/2024 this week. TH and Friday were fine. But, Tonight [Sun PM], and yesterday [Sat AM]...after taking my shot I had a bad reaction. It felt like a burst of pain hit the small of my back then pulsated up my spine quickly toward my head....shooting off toward my heart causing sharp pain briefly there, while the pulse continued up my spine to my head where I got an immediate strong headache. The pulse and pain stopped elsewhere, and just stayed in my head 15-30 minutes, then that pain was done. Scary.
Note. In each case, I did not have the symptoms until after the shot, I made a quick, brief few bits of exertion. First time... I bent over and played with my dog for 30 seconds. The next day, I merely stood up, went into the kitchen then back to my chair. [10-12 steps] After each bit of exertion, is when the symptoms occurred.

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No, thank you! I stopped Tymlos, because I’m not interested in experiencing negative symptoms like I had with the first injection. It’s not normal, and I was also concerned about longterm challenges, that they aren’t even aware of. I’m too scared to inject myself again, after what I experienced.

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