I’m afraid stage 4 esophageal/lung Her2+ PD-l1+

I'm sorry to hear of your recent diagnosis.

I am 6+ year survivor of Stage 4 squamous cell esophageal carcinoma. While my rigorous treatments have somewhat diminished the quality of my life, it's been worth it the struggle as it's given me more time with my loved ones, friends and colleagues.

As another respondents have mentioned, you should avoid consulting "Dr. Google" as it oft times can provide you with voluminous and conflicting information. The various AI apps like ChatGPT, Grok and DeepSeek are also useful to learn more about your disease and various approved and investigational therapies. However, they are still prone to providing false or misleading informations on your topic of investigation due to "hallucinations". You should not rely upon for these apps for medical advice, diagnosis or treatment recommendations. They may be of use to help you hold more meaninful and insightful conversations with your oncologist about y
The most effective treatments for your disease.

You should access various patient forums like Mayo and SmartPatients for useful tips from other patients re their experiences with various therapies and management of complications.

Hopefully, you have confidence in your treating oncologist. He or she will or should order biopsies of your primary tumor(s) and accessible nodes for immunohistochemistry and molecular genetic analysis. This will help guide the selection of the most effective chemo and immunotherapies for your tumors and nodes.

If you have not already done so, I suggest that you seek a second opinion on your case from one of several cancer centers such as Mayo, MD Anderson or MSK.

As to your treatments, they will be rigorous, physically and mentally taxing, Typically, initial therapy is targeted radiotherapy to "de-bulk" your tumor load, followed by various chemptherapies, FLOT, FOLFOX, FOLFIRI etc
Your chemotherapy regimen may often be supplemented with the addition of various oncogene targeted adjuvant immunotherapies, targeted small molecules and developing cellular therapies.

Esophagectomy is often recommended and can lead to prolonged recoveries, but is associated with improved clinical outcomes and overall survival.

It's critically important that you adopt and maintain a positive mental attitude (PMA). Adopt the mindset that you own your disease, it doesn't own you.

Try to maintain adequate nutrition and hydration, which may require the placement of a NG or G-tube. You should request a consult with a nutritionist to help with the selection of appropriate nutritional regimens.

You should engage in light exercise such as much as possible via walking or use of exercise treadmills/ellipticals and use of light weight resistance training.

The road ahead of you is going to be rough, but with the continuing innovations in various therapeutic modalities there is hope for improved disease control, prolonged survival and rendering your disease to a chronic/manageable condition or potentially cured.

I wish you all the best in the upcoming battles with the beast.

First so sorry for your diagnosis. Next forget google so much misinformation about survival rates and treatments. Talk to your oncologist if you don’t like what they have to say get 2nd opinion. Don’t give up or give in so easily. Need to ask questions about everything that’s happening to you. I had stage 3 esophageal cancer went through flot treatments. That’s 4 chemotherapy treatments then surgery then 4 more chemo treatments. Now I couldn’t eat or drink anything for 6 months. Had a j tube put in for fluids and nutrition. Got me through until I could eat again after surgery. This isn’t easy by any means. But if you want to live make a choice of having a positive attitude that you want to live for yourself and your family. Family will hopefully be a big influence for you to live also. There will probably be other people on here that will provide there input also. We all care and don’t want anyone to give up. Any questions please ask. Hoping the best for you and your family!! Scott

First so sorry for your diagnosis. Next forget google so much misinformation about survival rates and treatments. Talk to your oncologist if you don’t like what they have to say get 2nd opinion. Don’t give up or give in so easily. Need to ask questions about everything that’s happening to you. I had stage 3 esophageal cancer went through flot treatments. That’s 4 chemotherapy treatments then surgery then 4 more chemo treatments. Now I couldn’t eat or drink anything for 6 months. Had a j tube put in for fluids and nutrition. Got me through until I could eat again after surgery. This isn’t easy by any means. But if you want to live make a choice of having a positive attitude that you want to live for yourself and your family. Family will hopefully be a big influence for you to live also. There will probably be other people on here that will provide there input also. We all care and don’t want anyone to give up. Any questions please ask. Hoping the best for you and your family!! Scott

I'm sorry to hear of your recent diagnosis.

I am 6+ year survivor of Stage 4 squamous cell esophageal carcinoma. While my rigorous treatments have somewhat diminished the quality of my life, it's been worth it the struggle as it's given me more time with my loved ones, friends and colleagues.

As another respondents have mentioned, you should avoid consulting "Dr. Google" as it oft times can provide you with voluminous and conflicting information. The various AI apps like ChatGPT, Grok and DeepSeek are also useful to learn more about your disease and various approved and investigational therapies. However, they are still prone to providing false or misleading informations on your topic of investigation due to "hallucinations". You should not rely upon for these apps for medical advice, diagnosis or treatment recommendations. They may be of use to help you hold more meaninful and insightful conversations with your oncologist about y
The most effective treatments for your disease.

You should access various patient forums like Mayo and SmartPatients for useful tips from other patients re their experiences with various therapies and management of complications.

Hopefully, you have confidence in your treating oncologist. He or she will or should order biopsies of your primary tumor(s) and accessible nodes for immunohistochemistry and molecular genetic analysis. This will help guide the selection of the most effective chemo and immunotherapies for your tumors and nodes.

If you have not already done so, I suggest that you seek a second opinion on your case from one of several cancer centers such as Mayo, MD Anderson or MSK.

As to your treatments, they will be rigorous, physically and mentally taxing, Typically, initial therapy is targeted radiotherapy to "de-bulk" your tumor load, followed by various chemptherapies, FLOT, FOLFOX, FOLFIRI etc
Your chemotherapy regimen may often be supplemented with the addition of various oncogene targeted adjuvant immunotherapies, targeted small molecules and developing cellular therapies.

Esophagectomy is often recommended and can lead to prolonged recoveries, but is associated with improved clinical outcomes and overall survival.

It's critically important that you adopt and maintain a positive mental attitude (PMA). Adopt the mindset that you own your disease, it doesn't own you.

Try to maintain adequate nutrition and hydration, which may require the placement of a NG or G-tube. You should request a consult with a nutritionist to help with the selection of appropriate nutritional regimens.

You should engage in light exercise such as much as possible via walking or use of exercise treadmills/ellipticals and use of light weight resistance training.

The road ahead of you is going to be rough, but with the continuing innovations in various therapeutic modalities there is hope for improved disease control, prolonged survival and rendering your disease to a chronic/manageable condition or potentially cured.

I wish you all the best in the upcoming battles with the beast.