If a doctor tells you a spot he found has metastasized?

I’m sorry for you & your situation. It’s extremely difficult having a non compliant family member. In answer to your question, yes metastasis always come from cancer. This is called having an unknown primary, also called an occult tumor, when this happens they do more imaging to find where the primary is, so they can tailor the treatment to the specific cancer. Metastatic disease is no longer the death sentence it once was, many of us are living with it, but you do have to get treatment when necessary.
I’m sorry not to be more helpful. My mom reacts as your brother, & then isn’t honest with us. I understand the anxiety & worry that goes with this situation. Take care of yourself, best wishes.

Thank you so much for your reply. I just know my brother and he has not been himself lately. He's usually a comedian, he'll have everybody in the room laughing the whole time he's around, but he's been really quite and staying to himself. He's usually just like me, we cant sit still long at all, but he ain't doing anything. I'm scared for him because they may start a treatment and by then it'll be to far gone. And I'm kinda frustrated with his wife because she was with him when he was told this but keeps telling me that they sent him home and told him to follow up, but 45 minutes before that she told me they're admitting him. I know shes just doing what my brother wants but this is serious and his sister (me) needs to know. I appreciate your reply!

Hi. Sorry for what you and your brother are going through.
Some people do have a complicated relationship with hospitals.
It sounds like your brother does have a cancerous growth, and that growth is in more than one place. It would be good for them to do a proper metastatic workup and a biopsy.
There's other structures in the head besides the brain. There are the coverings/skins of the brain (3), there's blood vessels, there's the bone, and outside; the skin and some fat.

Does your brother have a person that calms and grounds him? Maybe him sitting with that person and talking may help.

That definitely wouldn’t be me, I’d stress him out more probably (not meaning to of course) But our older brother Billy would be good for calming him. I just know he’s not himself lately. He would usually be the life of the party making everyone laugh, but has been quite and staying to himself. I just don’t know if he’s hurting somewhere and not telling us or what. Thanks for your reply

Maybe you could ease your brother around to a more academic (and less emotional) stance by trying to encourage him to get more information and make decisions based on that. I would ask the doctor what the evidence is for metastasis, and how they know it's not a primary tumor. Then I'd ask for clues as to why they believe its a tumor and not a vascular thing or something else. Then, of course, what other tests will provide more definitive information. I'm sure he feels like he's been thrown under a bus ... maybe it would help him to feel like he's fighting back without giving in. It sounds like he might be scared and hiding it behind defiance.

It doesn't have to be you, it could be anyone, even a non-relative.
I think you also need to spend some time around your grounding person, if you have one or find one. This will be heavy on all of you.
A lifetime ago, when the love of my life was still alive, my life felt lighter. It is amazing what a person's presence can accomplish, even in silence, even electronically. That feeling of being grounded and some level of clarity of thought, I wish that for you and your brother.

Also, kudos for being brave and sharing your concerns. Thank you

Very good advice, thank you!

Thank you