Concerned about the side effects of anastrozole

I have just received  a call from my internist telling me that my ColonGuard test was positive and that I need to have a colonoscopy. Apparently this test has an 80% false positive rate, so I don't even know why I bothered. I am terrified of the colonoscopy, assuming that I have another cancer site. Also, for the last 4 months I have been developing very painful sore throats and mouth sores. I have only been on Arimidex for 9 months. The joint pain, hot flashes,fatigue, etc. were tolerable but I cannot continue feeling like I have the flu every other week. I will see my oncologist in 3 weeks. I am totally anxiety riddled and am being treated for depression (an ongoing problem) although the depression hardly ever goes away.  I appreciate your response. I generally avoid support groups ~ They either scare me or make me more nervous about my breast cancer.

I am happy that you’ve adjusted to Anastrozole and are investing in a proactive mode. The joint pain and dry skin were too much, as well Aromasin.
I’ve been on Letrozole going on 4 months and it has literally been 9 days that I realized my joint pain has dramatically lessened — and I am thrilled!!! I still have joint issues in my hands and wrists, but I’m feeling hopeful and if things continue like this, I can tolerate this for my 5 year commitment.
I am so relieved.

I've been on Anastrozole for almost 2 years. At first I really suffered from joint pains, but that eased with time. It has severely affected my bones and my hair seems to be falling out a bit more than I'd expect, but I don't know if that's age or the Anastrozole. It also has caused hot flashes, skin dryness and fatigue. I'm post menopause, so some of these issues I would expect with age, but I never really experienced hot flashes before and my skin was a bit dry, but nothing like it is now. Still very thankful this option is available though and have no plans of stopping.

Hello @rosiemolano,

Welcome to Connect. I can only imagine what a rough journey you've been on for the past two years. Thank you for sharing and reaching out to the Connect community. While we wait for others to share their insights and thoughts, I thought you might wish to read these two studies I found online, about management of aromatase inhibitor induced musculoskeletal symptoms:

– http://www.croh-online.com/article/S1040-8428(16)30235-9/fulltext
– https://source.wustl.edu/2011/07/vitamin-d-relieves-joint-muscle-pain-for-breast-cancer-patients-2/

@rosiemolano, we'd really like to get to know you better; would you share a few more details? How are you managing the side effects at present?

I would recommend that women with hormone positive breast cancer ask their oncologists to check their hormone levels before using the drugs, during and after. I was unable to take the drugs due to side effects, but was always worried about my Estrogen levels (due to estrogen positive breast cancer). At my two year checkup (I have check ups each 6 months with various tests) I asked if they could check my Estrogen levels for me. They usually don't because they assume most breast cancer patients are taking the pills. Well..........my estrogen levels are no where to be found, they are virtually non-existent. I did lose 25-30 pounds and have been fairly strict with diet, exercise, vitamins and the like. Looks like my body decided for me not to have estrogen on it's own! I'm not saying that it will stay that way or that I'm very confident the cancer won't return that's feeding on that estrogen BUT.......if you're having a really hard time with the aromatase or tamoxifen, perhaps getting a baseline on your hormone levels could be of some help. Also, despite not taking the pills.....I have hair thinning, some achy joints (not nearly as bad as when on the meds) and other symptoms of low estrogen. My bone scans show some slight loss but nothing like what I hear about with the meds. Just a thought that might help some women to move forward if the pills are making your life too difficult.

yes, I have and just need some honest answers and reall attention to my complaints

I started Anastrozole immediately after my mastectomy in 2016, my oncol. did not discussed sideeffects. I did however notice he was overly concerned about my ankles and pain in ankles-I had no complaints. Now in 2018, I have sleepless nights, horrible depression,horrible joint and bone pain and my hair is thinning. I have grown my hair past my butt and it has been increasingly thin on top and throughout. I have a different Oncol. and it seems it takes an act of God to get her to switch me to a different pill. I have to take this pill x 10 years, don't think I will make it that long.

CORRECTION!!! mY BREAST CANCER WAS DISCOVERED IN SUMMER OF 2016, NOT 2017. TIME FLIES!!

I have been taking Anastrozole for three years. I have ongoing, constant hot flashes and have recently noticed that my hair is thinning out and I have a couple of bald patches. The only thing that makes me feel grateful is that i am only dealing with those two side effects. I've had three colds this winter because even though I go out bundled up when it's cold out, I still sweat a lot. Just horrible. I think that next winter I should wear a surgical mask every time that I go out in the cold.

Hope this works better for you. Don't think I mentioned my hair, which was always thin, is now much thinner than ever - but I guess that should be the least of my worries!