Anyone taken Plaquenil (hydroxychloroquine) to reduce prednisone?

Posted by joancanzan @joancanzan, 23 hours ago

Has anyone taken hydroxychloroquine for prednisone reduction?

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) Support Group.

I’ve been taking hydroxy for 20 years, but not for PMR. I have never had. Bad reaction to it, but it didn’t help at all when I was diagnosed with PMR two years ago. Still taking hydroxy along with prednisone and probably will for the rest of my life.

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Hydroxychloroquine plus methatrexate for several years helps reduce Lupus Flares. I try to stay away from predisone but I have it in case needed.

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Here are a couple of related discussions about Plaquenil (hydroxychloroquine) and PMR:
- Are you taking Plaquenil (Hydroxychloroquine) for PMR? https://connect.mayoclinic.org/discussion/are-you-taking-plaquenil-hydroxychloroquine-for-pmr/
- Treating PMR with Prednisone and Hydroxychloroquine: https://connect.mayoclinic.org/discussion/treating-pmr-with-prednisone-and-hydroxychloroquine/

@joancanzan, am I understanding that you were given hydroxychloroquine to help with tapering off of prednisone? How is it going?

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Profile picture for hammock117 @hammock117

Hydroxychloroquine plus methatrexate for several years helps reduce Lupus Flares. I try to stay away from predisone but I have it in case needed.

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Thanks for this info, I tried both of these drugs at the beginning of my PMR journey and both caused pain in my right side. So, we stayed with Pred. I am currently on 1 mg of pred every other day. Best I have been in 3 years. Should I expect very adverse effects from this low dose? Highest dose I ever took was 10 mgs about a week, with some small infections occurring ( eye and nose). Went to 5 mgs for a long time and then started the descent. Been on 1 mg for a while now. 1/2 appears inadequate after a few days. Appears 1 mg every other day is the lowest dose with the least pain. Thoughts?

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Profile picture for vandyms1974 @vandyms1974

Thanks for this info, I tried both of these drugs at the beginning of my PMR journey and both caused pain in my right side. So, we stayed with Pred. I am currently on 1 mg of pred every other day. Best I have been in 3 years. Should I expect very adverse effects from this low dose? Highest dose I ever took was 10 mgs about a week, with some small infections occurring ( eye and nose). Went to 5 mgs for a long time and then started the descent. Been on 1 mg for a while now. 1/2 appears inadequate after a few days. Appears 1 mg every other day is the lowest dose with the least pain. Thoughts?

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You are blessed that 1mg works. Stay with it.
I have several autoimmune diseases..many specialists..at one time I had 40 mg shot...then 20mg then stop down.
I am blessed by God to be as active as I am.
Prayers to you.

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