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How long to wait between Evenity and Reclast

Posted by aspirecreative @aspirecreative, 2 days ago

I have finished Evenity and plan to start Reclast. I have heard different opinions : some say necessary to start Reclast 1 month after or will lose gains right away; others say it is ok to wait 2 or even 3 months. The latter allows for bone mineralization to complete before Reclast seals in gains. I don't see that Amgen has a recc about this. I had a significant spine gain (15%), not anything in hip or femur, but also no loss. My understanding is that Evenity stays in your body for 60 days, so it seems like waiting for the mineralization makes sense. Has anyone seen research on this? Thank you.

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oopsiedaisy | @oopsiedaisy | 2 days ago

There are a lot of opinions judging from the other thread. I like to use science-based evidence for my decisions but also weigh my own thoughts about the matter. I will be getting my last shot in two weeks and was hoping to have a break before the Reclast (3 months). However, I have decided to go with what my doctor recommends. She is testing my CTX levels next week and I assume this will play a role in when to have my Reclast infusion.

If it’s high then I’ll need it earlier as the bone remodeling process will ramp up once Evenity stops.

Personally, I feel that it doesn’t make much of a difference whether it’s 1 month or 3 months. Going any longer than that does appear to make a difference based on the studies in the thread posted by njx58.

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patwerthman | @patwerthman | 19 hours ago
In reply to @oopsiedaisy "There are a lot of opinions judging from the other thread. I like to use science-based..." + (show)
Profile picture for oopsiedaisy @oopsiedaisy

There are a lot of opinions judging from the other thread. I like to use science-based evidence for my decisions but also weigh my own thoughts about the matter. I will be getting my last shot in two weeks and was hoping to have a break before the Reclast (3 months). However, I have decided to go with what my doctor recommends. She is testing my CTX levels next week and I assume this will play a role in when to have my Reclast infusion.

If it’s high then I’ll need it earlier as the bone remodeling process will ramp up once Evenity stops.

Personally, I feel that it doesn’t make much of a difference whether it’s 1 month or 3 months. Going any longer than that does appear to make a difference based on the studies in the thread posted by njx58.

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@oopsiedaisy Is recast what’s suggested for after Evenity ?

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kristie2 | @kristie2 | 18 hours ago
In reply to @patwerthman "@oopsiedaisy Is recast what’s suggested for after Evenity ?" + (show)
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@oopsiedaisy Is recast what’s suggested for after Evenity ?

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@patwerthman it all depends on your T score. When I started Evenity my T score was -4.6 after Evenity it was -3.3.
My endocrinologist wanted to gain more bone density so I took 2 doses of Prolia for a gain of only .1 my DEXA was only -3.2 so I went on to reclast.

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patwerthman | @patwerthman | 11 hours ago
In reply to @kristie2 "@patwerthman it all depends on your T score. When I started Evenity my T score was..." + (show)
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@patwerthman it all depends on your T score. When I started Evenity my T score was -4.6 after Evenity it was -3.3.
My endocrinologist wanted to gain more bone density so I took 2 doses of Prolia for a gain of only .1 my DEXA was only -3.2 so I went on to reclast.

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@kristie2 so have you had your Dexa scans each a year apart?

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