How long does it take to recover from Metformin Fatigue

@cewmyers57 I don't want to sound jaded, but I guess I am due to the fact that I see all the drug reps with their leather briefcases full of "goodies" waltzing in and out of the doctors office while their waiting rooms are full of their patients waiting to be seen. Aside from Big Pharma influence on how and with what we are being treated, I have a problem with setting a universal "one-size-fits-all" number that determines which side of diabetes you're on. No 2 people are alike and we all show up with our own individual bodies with all their unique facets, so how can you draw such a line in the sand. Should there be "guidelines", of course, but mandating that every one on earth has to be at a certain number set in stone is unfair and unrealistic . . . but it does sell medication.

@leigha67
I have other health issues (GBS). Still, I've been renovating my place and seem to hit a "wall".
It feels as if the very cells in my body have run out of energy. My breathing gets ragged. I have to stop what I'm doing...NOW. I also seem to get MADDENING itching, at a different spot, each time.
I had a pancreatic attack, 18 years ago and biked my way out of the diabetes I was diagnosed with. But even then, I noticed that "wall". It prevented me from biking as I wished. I could do half, basically, of my normal rides. I'd get so tired and had to "limp" home.
I unilaterally stopped the pills and the problem went away, soon after. So fun watching my nurse and doctor argue about whether I'd just "cured" myself.
"Nurse. You know darned well there's no cure for t2 diabetes."
"Well doctor. They had diabetes and now they're normal. What would yo call that?"
"I don't care what you call it, there is no cure for diabetes!" Etc.
I'm now in my late 60s and biking my way out isn't an option. However, with a grain mill, organic gardening and of course, THCv, my A1C has been a steady 6.2 for 6 months. Down from 11.0, a year ago!
6.2 is not great. Not as good as the 5.6 I achieved on CBG isolate (800mg/day). But I got a medical grow license from Health Canada and just harvested my first THCv crop. This has tripled the dose of that very expensive cannabinoid. DEFINITELY engaged my ECS (endocannabinoid system), and my symptoms have all but disappeared.
My question now is: at what point do I try to "work without a net" and stop the pills?
This fatigue hampers everything I try to do. And while it may well be linked to the Guillain Barre, I can't help thinking the metformin is the cause.
My doctor is in her first months, as my former doctor ran away to England to get married.
She has no experience, even if she's very smart.
Anyway. I'm tempted to pull the trigger. Almost as much as I'm worried about my glucose spiking.
Maybe this summer...

@morgan561
Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes-A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study
https://diabetesjournals.org/care/article-abstract/39/10/1777/129/Efficacy-and-Safety-of-Cannabidiol-and
just saying...

RESULTS

Compared with placebo, THCV significantly decreased fasting plasma glucose (estimated treatment difference [ETD] = −1.2 mmol/L; P < 0.05) and improved pancreatic β-cell function (HOMA2 β-cell function [ETD = −44.51 points; P < 0.01]), adiponectin (ETD = −5.9 × 106 pg/mL; P < 0.01), and apolipoprotein A (ETD = −6.02 μmol/L; P < 0.05), although plasma HDL was unaffected. Compared with baseline (but not placebo), CBD decreased resistin (−898 pg/ml; P < 0.05) and increased glucose-dependent insulinotropic peptide (21.9 pg/ml; P < 0.05). None of the combination treatments had a significant impact on end points. CBD and THCV were well tolerated.
CONCLUSIONS

THCV could represent a new therapeutic agent in glycemic control in subjects with type 2 diabetes.

Dose were extraordinarily small: 10mg/day

GW Pharmaceuticals 2016

PubMed:
27573936

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