Hot flashes after Lupron: 7 months and counting

Posted by anosmic1 @anosmic1, 2 days ago

I had a single Lupron shot 7 months ago before beginning radiation. I'm 68, Gleason 9, had surgery 11/11/24. My PSA was still low (0.04) in October but trending the wrong way so we chose radiation. Lupron shot 10/15/25, and 39 radiation sessions. I am undetectable for 2 months.

But the hot flashes continue. The Rad Onc gave me a suggestion for a menopause drug to combat it, and that worked but only after the hot flash began. I'd love to not wake up 2-3 times a night with heat radiating off my body. Summer has started in Phoenix, and I don't need internal heat when it's 110 outside.

And now, back to our regular programming.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

my guessis you still have Lupron circulating..I hate night hot flashes too. I have tried putting a small cooler with ice and water beside my bad.. when the hot flash begins, I just put my forearm into the cooler..it does stop the hot flash pretty quick, but you are left with cold arm..but at least is not another drug to keep up with

REPLY

I read somewhere that for Lupron one can expect recovery to happen after the same amount of time passes as was the period of time that it was used - for example, if one used Lupron for 6 mos, one can expect side effects to last for the next 6 mos after one stops using it. I do not know if that is true - just something I read somewhere.

REPLY

I had my last leuprolide injection one year ago. I discontinued oral abiraterone with prednisone shortly thereafter. This was after approximately 2.5 years of continuous treatment. My hot flashes have definitely reduced in frequency and somewhat in intensity, yet I still am awakened in the middle of the night frequently or must turn on the ceiling fan when watching TV in the evening. My testosterone level remains undetectable and I attribute the hot flash persistence to this!

REPLY

You mentioned having “a single Lupron shot 7 months ago before beginning radiation.”

Lupron is administered in 1, 3, 4, or 6-month injections. Was yours a 6-month injection? (If so, the effects may linger for a few months longer than the injection was for - until your testosterone levels recovers.)

> what was your testosterone level before the Lupron injection?

> what is your testosterone level now?

It may be a still-low testosterone level (and what that causes) that results in the side-effects you’re still experiencing.

REPLY
Profile picture for surftohealth88 @surftohealth88

I read somewhere that for Lupron one can expect recovery to happen after the same amount of time passes as was the period of time that it was used - for example, if one used Lupron for 6 mos, one can expect side effects to last for the next 6 mos after one stops using it. I do not know if that is true - just something I read somewhere.

Jump to this post

@surftohealth88

I am at 13 months since my last 3-month Lupron shot and my very severe side effects have just started to abate. I had very severe headaches, muscle pain, joint pain, bone pain, continuous cold sweats and occasional hot sweats. These typically occurred 24 hours a day with no let up. l believe I would have died or killed myself if I had one more Lupron shot. My cardiologist felt that the Lupron was also harming my heart. I am 83, now have a 115 testosterone level, and PSA < 0.03 for last 6 months. Before treatment I had a 11.0 PSA, 3 ea. 3+3 and 1 ea. 4+4 Gleason measurements. Treatment was 44 radiation treatments and 4- months of Lupron.

REPLY
Profile picture for pesquallie @pesquallie

@surftohealth88

I am at 13 months since my last 3-month Lupron shot and my very severe side effects have just started to abate. I had very severe headaches, muscle pain, joint pain, bone pain, continuous cold sweats and occasional hot sweats. These typically occurred 24 hours a day with no let up. l believe I would have died or killed myself if I had one more Lupron shot. My cardiologist felt that the Lupron was also harming my heart. I am 83, now have a 115 testosterone level, and PSA < 0.03 for last 6 months. Before treatment I had a 11.0 PSA, 3 ea. 3+3 and 1 ea. 4+4 Gleason measurements. Treatment was 44 radiation treatments and 4- months of Lupron.

Jump to this post

@pesquallie
I am so sorry to hear about your prolonged suffering caused by Lupron 😢, that is just terrible what you had to endure ...

Sending you the best wishes for fast forward resolution of ALL side effects and for forever PC remission ! 🍀✨

REPLY

Almost 2 years since my last "Eligard" shot. Still getting most all
side effects.

REPLY
Please sign in or register to post a reply.