Hormone that may help inflammation

Fascinating. But I think we agree that these therapies need to come to the people sooner rather than later.

The vagus nerve has been getting a lot of attention too, with regard to inflammatory conditions.

Alternatives to these heavy-duty drugs is necessary and welcome.

@diverdown1 Interesting article! What was your main ‘take away’ from the article?

@beachesanddreams I completely agree with you. Polyvagal therapy is getting a lot of attention and it makes sense to me. There may be a lot of folks that do not agree with me, but I believe, truly, that when a person's body is in fight/flight mode for too long, it causes a the body to say "enough." There is research showing that a lot of autoimmune diseases and inflammatory issues come from trauma. I am not talking about PTSD but trauma from early childhood experiences and the survival skills that people acquire over the years. I also believe that genetics can be involved. I know that medications that target my dopamine receptors and SNRI's that target norepinephrine have helped me function. Anyway, I appreciate all of you. I do not feel as alone and this helps me every morning.

@becsbuddy It is interesting! I believe that cortisol, trauma and stress play a huge role in inflammation. I just replied to @beachesanddreams about it.

So happy to see scientist, working on hormonal drivers of inflammation. I was diagnosed with RA six weeks after giving birth to my daughter, or after the good hormones grow up. And I started having massive flares and an intensification of my disease course at menopause. This seems to be such an important part of the picture for me. This research can’t come soon enough.

My personal experience with childhood trauma and low cortisol took many years to be recognized and understood. Now, nearly 50 years later, neurology, endocrinology, hematology, and scientific research more broadly have begun to understand the complex relationship between chronic inflammation in the brain and its wide-ranging effects on nearly every organ in the body.

Many of Professor Robert Sapolsky’s lectures, available on YouTube, as well as his books, explain in detail the critical role of the HPA axis and the endocrine system in these processes.

@diverdown1 There are studies out there that say the same, especially with regard to stress. I have also read on rheumatology websites that ANA titers in particular can actually fluctuate over time.

I put the website to Dr. Kevin Tracey on another discussion thread, and I’ll pop it here, too. The FDA recently approved his vagus nerve therapy for certain inflammatory conditions.
https://feinstein.northwell.edu/institutes-researchers/our-researchers/kevin-j-tracey-md

@sweetundine

I 100% agree!

@beachesanddreams is there any chance of purchasing one of these Vegas? Nerves therapy machines? Please say yes thank you

@annpeters
There are several types of vagus nerve therapy currently available. It is advisable to thoroughly review the available options and carefully consider the potential risks and side effects before initiating any treatment.

Additionally, some vagus nerve therapy devices on the market have not consistently demonstrated the expected clinical outcomes.

Vagus Nerve Stimulation (VNS)
https://my.clevelandclinic.org/health/treatments/17598-vagus-nerve-stimulation
Vagus Nerve Stimulation
https://pmc.ncbi.nlm.nih.gov/articles/PMC4017164/