Anyone had T-DM1 trastuzumab emtansine (Kadcyla): What side effects?

I'm tagging a few members who have had treatment with T-DM1 trastuzumab emtansine (Kadcyla), like @zeerj @maggieb892 @boathouse @simondsa1, who can share their experiences.

@terratta, have you started Kadcyla? How are you doing?

I experienced two side effects while on Kadcyla. One was quite simple and the other potentially more serious. I experienced some constipation when I started the treatment. I wasn't effected much because my diet was strong in fruits and vegetables, lots of fluids and fiber. I was able use my diet to keep the constipation at bay. I was very strick in maintaining a healthy eating style.

The other issue which requires close monitoring is the effect the chemo has on the liver. The liver enzymes can elevate beyond healthy levels. Mine did toward the end of my treatment. In fact I missed my last treatment because my number was one above the limit.

I hope that you will be closely monitored and keep in touch with your team at any changes in your condition.