Has anyone taken Lynparza?

I was on Lynparza for a year. It is very expensive, but my insurance covered it. I was on because of BRCA2 and HER2+ in my tumor. I also completed most of my chemo. 13 rounds, and since i developed pancytopenia, they decided Lynparza would be best as i had not had three of the AC treatments. Only 1. They are the team of oncologists who met at COH to talk about special cases needing more attention.
Looking up Lynparza, it has been used in Metastatic cases. I was not metastatic, but with that BRCA2 gene it needs extra review depending on which cancer we have.

I'm currently on Lynparza, hopefully ending at the end of the year. I'm on Lynparza because I'm TNBC BRCA2+ and had already completed chemo, bilateral and radiation. I started lynparza while working and my commercial insurance covered the cost of the med. But I'd already started the process to retire and the cost was only partially covered by Medicare. The following year i was eligible for manufacturer assistance. I would not have been able to cover the cost on my social security.

I came across this again. Too few people are getting Lynparza. In posts, I have noted it is part of mediatized cases of stage 3 or 4. That brought to mind how all insurance companies need to cover research hospitals for anyone who has cancer. Up to date treatments are standard. A friend of mine just passed away as her insurance did not cover research hospitals. My cancer treatment for the breast was all about what has proven to work.

Met with oncologist yesterday, SGPT levels are rising; but not at dangerous levels. I'll only be on the meds until the end of the year so she believes I should be fine. But we'll keep an eye on the levels. But all other lab levels were within normal levels - so I'm good.

I did not have that result. Just yesterday I had my first day of conditioning for my bone marrow transplant. We talked Lynparza. I finished it after 1 year in mid-June of 2023, He said my white cells and plantlets have still not reset. They continue going down. That is not an effect of Lynparza. It is the underlying TP53 mutation.
I do think checking with your DR is perfect. Keep us posted bpknitter53.

Has anyone had increased ALT SGPT (which I think has to do with liver process)? I'm on Lynparza 100mg twice a day for TNBC BRCA2+. I've been taking the pill since July 2023 and believe I'm only going to be on a few more months. Previous lab work had the ALT SGPT within normal ranges, it's started creeping up and is just above normal range. I'll check with dr. (see her tomorrow) to see if level is still within OK range and will it recover after I'm off the pills.

Just wanted to see if anyone else experienced elevated lab results and if subsequent lab results showed recovery of the ALT SGPT test.

I look forward to hearing. I was on 3 drugs for most time i was on Lynparza. Side effects lessened after I got off each.

I've been on Lynparza now for just about two months - my only side effect appears to have been when taking the pills on an empty stomach. I had a short bout of the runs when taking the pills early in the morning on an empty stomach. Started eating before taking the pills and now I'm good, I can actually take the pills with food and still be good so I've changed the time I take the pills. I'm getting ready to have my first dr. visit with lab work after starting the pills - so we'll see what numbers I have. My dosage might get increased as I believe I'm on the lowest dosage prescribed. I'll update after my dr. appt which is next week.

I was on Lynparza from June of 2022 and June of 2023. I had the same dosage as BPknitter.
Side effects? I was also given 18 infusions of Herceptin/Perjeta during this same time from March-March. I had the genetic test and had Brca2. My tumor was HER+. My Medical oncologist and the team at City of Hope gave me Lynparza as my 16 rounds of chemo were shortened to 13 rounds due to side effects.
So, for side effects I had an ongoing slight metal taste in my mouth till a few weeks after my last Lynparza pill. Neuropathy in my fingers continued. Honestly though, I had breast surgery in Feb and Dec of 2022 and I know those as well as the meds combined for the joint, shoulder and trigger finger. Most of those side effects are negligible now. How did the drug help me? Time will tell.

I have regularly been on breastcancer.org, as a friend suggested I join after my diagnosis, As my active treatment ended, I was looking up Ovarian cancer as my sister was diagnosed in July. I was finding many studies put out by the Mayo Clinic that were interesting. I saw I could join and decided to do it. A friend of mine is being treated at MD Anderson in Texas, another sister at Roswell Park in NY and Cleveland Clinic.
I am being treated at the City of Hope in Duarte.
I have found in Mayo connect an interesting mix of info. I do not have to be treated at Mayo to get a benefit from hearing from others and sharing with others as time allows.