Has anyone had experience with duloxetine and gabapentin? Duloxetine a

@uncavan, I think there are a lot of members who may have some experience with each of medications you mentioned but not sure how many have experience with the different combinations. Here's a search of Connect using "Duloxetine and Gabapentin, Duloxetine and Tramadol" if you want to scan through the discussions and Comments while you wait for members to respond -
https://connect.mayoclinic.org/search/

@johnbishop I have been using 20mg of duloxetine for several weeks for my pn. It has cut the pins and needles effect in my legs and feet by approx. 80%.

Those 2 drugs are a part of my daily consumption of prescription meds, along with 7 others.

@mrmacabre Which 2? Any side effects?

@uncavan
I used duloxetine and tramacet once, and I had good relief of my neurapathy, but I stpped taking it because the effects wore off in a few days. I also developed extreme perspiration that was very uncomfortable. I still take the tramacet, and that helps somewhat. Pregablin hasn't helped with my numb feet, but I occasionally take a pill at bedtime because it gives me an good night's sleep.

Thank you.

@uncavan Duloxetine and gabapentin. I take so many different drugs everyday that I have no way of knowing if 1 or 2 of them are having side effects on me.

@mrmacabre Boy, do I understand that!

I have taken Duloxitine (Cybalta) but had to stop. As it produced severe anhedonia. It did help with the pain however.

@suetex Sorry to hear that. Glad you're off it now. Life's too short to be miserable.