Has anyone done Plasmapheresis for WM?

Hi RanchGal. I had it done just a couple months after finding out my low energy levels was WM. (Feb of ‘25) After just my 1st blood cleansing I felt like a new person. I was told they normally do three cleansings, but I felt so good after two, they were able to discharge me. I have been like an energizer bunny since. Mine was through the jugular vein, which was a crazy process. Some discomfort when they were putting the catheter (yes…that’s what it’s called) into my neck. But then I had no trouble sleeping with it there and no issues up until when they went to remove it. And that’s when there was a lot more discomfort because it’s like my skin was starting to heal around it. But they put some lubrication on and was able to pull it right out. I was told if they have to do it again, they will use both my arms, and if it requires another procedure down the road, they will probably just put a port in my chest. You will be amazed at how good you feel. Best wishes to you!

Hi Ranchgirl. That procedure is common in WM to reduce blood viscosity by filtering out the IgM molecules but not blood cells that are making it. It is not a cure, but a temporary reduction in IgM since the blood cells are still there. Only treatment will provide longer lasting reduction. A WM experienced doctor should be familiar with this. Check IWMF site for a lot of information and dedicated forum.