Hand and Foot Syndrome - any suggestions?

Here's the study: https://ascopubs.org/doi/10.1200/JCO.23.01730

Been using the Udderly Smooth. Haven’t combined with Voltaren but I’ll try. Thanks.

Try using Voltaren (topical pain reliever for arthritis) or a generic at least twice a day, then slather hands and feet with Udderly Smooth 20% urea or other super thick cream. Let it soak into your hands. You can put your socks on over the cream.

I had chemo and radia treatments hands & feet are numb all the time Said something to the doctor he said it would go away with time well I am year out and no changes. Can not write have to print everything but life goes on Mayo is doing a research study on this issue They are just starting All i have done is sign release papers at this time Might want to look into this I guess if I have numb feet and hands it is a trade off as I am alive and cancer free so far

Taking capecitabin pills. Two weeks on one off. Started at 4 pills in the morning three at night. Hands and feet are peeling and cracking like a bad sunburn. Dr reduced me to 2 morning two at night. Symptoms got better but have come back. Interferes with my guitar playing and on bad days generally walking around (unless I wear thick socks). Capecitabin has been great otherwise as it has reduced my infusions from every other week to every 3 weeks. Time in the chair has been reduced also

The chemo that I got was Folfox 6, which includes 5-FU. The last treatment of 12 was 2 months ago. The situation with the skin on my hands and feet is only getting worse so far. I met with the oncologist today who said it's a very typical side effect of this type of chemo and with time it'll get better. Hopefully so and hopefully soon.
It does sound very much like HFS. This is the first time I'm hearing about this and did some research on it. Makes a lot of sense. I'll see what others share about this.
Thanks so much for responding. This is so helpful.

@mosk I believe you may referring to a side effect known as hand-foot syndrome (HFS). HFS is side-effect of some chemotherapy types. It is also called Palmar-Plantar Erythrodysesthesia or PPE. It affects the skin on your hands and the bottom of your feet. It usually starts with tingling or swelling of your skin and can become painful, red and numb.

I moved your question to this related discussion where members like @sallyg @adanab @seathink @mjjc are talking about hand and foot syndrome.
- Hand and Foot Syndrome - any suggestions?
https://connect.mayoclinic.org/discussion/handfoot-syndrome-any-suggestions/
Have you finished chemotherapy treatments? What chemo were/are you getting?

So I read in hear somewhere where some people are getting or have gotten peripheral neuropathy after stopping chemo. Definitely sounds like you have some numbness like what I get in winter without the chemo that is reynauds syndrome. I would reach out to your oncology team and see if have suggestions on where you could go for therapy before it gets worse. Have you tried epsom salt baths and magnesium for the muscle cramps/locking? Maybe deep tissue massages as well?

I'm two months after finishing 6 months (12 times) of chemo and my skin feels like it doesn't belong to me, especially my hands, bottom of the feet and forehead. It feels more slippery than normal and I don't feel things normally. For instance, holding a pen is difficult, or when I walk it feels like I'm not making normal contact with the shoes or floor.
My fingers sometimes get locked in a certain position for 2-3 seconds.
Anyone ever experienced anything like this?
Thank you and wishing you all good health always!

@jbickler, neuropathy is a common side effect with some cancer treatments, especially certain types of chemotherapy. You might find this discussion useful:

- Need hope: Neuropathy from chemo https://connect.mayoclinic.org/discussion/needshope/