Don’t opt out. Atypical means something might be brewing, and between another biopsy & MRI you would know for sure. IF there is anything, it is very early. Now is the time to deal with it rather than waiting. It is the smart thing to do

The MRI will direct the biopsy to any area(s) of concern and give you the answers you need. This was the final preventative test I used to make the decision to start treatment. I'm currently about two weeks into my proton beam therapy and all is going well.

If it were me, I would take their recommendations and go with the biopsy but ONLY under sedation. Not being sedated during this procedure is the only negative I have with Mayo.

Wizard59: Hello. I completed 20 radiation treatments 5/2019 at Mayo Clinic and now on 18-months of Lupron. Had the biopsy elsewhere while sedated with no difficulties. The biopsy told the story of a definite need for treatment. Recommend considering getting a second opinion how all of your treatment and care is going with a focus on the need for a second biopsy. All the best to you in your search for the right path for care.
OUMike

Morning wizard69
I agree have the other biopsy but make sure they put you out this time I had a bad experience my first one as well can’t imagine doing it a week again

Was the MRI very uncomfortable? Do they manuver the probe around like they do during a biopsy? Is sedation something to ask for?

I experience was very negative
The doctor did say that they were going to numb the area of the anal but that only happened after the guy put the camera up my butt… and it was was dry !
I wish they had given me the choice of being put under or awake
I have shows active surveillance I’ve decided to go to a different medical facility when it is to be done a second time .
I would not recommend that doctor for that procedure to anyone
I would ask your doctor your choices before it’s done

Welcome to Connect, @kane59. Have you been diagnosed with prostate cancer or are you in the diagnostic process?

I'm in the diagnostic process. No cancer was found but I have A-typical cells that need further investigation, hence the rectal MRI. My biopsy experience was horrible! All the probe manuvering was excruciating. Will the MRI be just as grueling, request IV sedation? I'm trying to talk myself into no further testing is needed, have a good day!

At 46 years old I started 3 years of biopsies and by the third year felt like a hunted animal. At the same time my PSA was rising to 7 or above. Once a positive finding for cancer was determined, only then did I undergo a prostatectomy. I’ll admit this was a very trying time for me. The diagnostic biopsies although uncomfortable, I felt the bigger issue was determining the course of action when the biopsies was positive. That was 34 years ago, and still cancer free.

Fairway5, can you explain the procedure involved with the rectal MRI? Is there constant manuvering of the probe? Is it as painful as the biopsy? Is sedation a good option?

Getting older sucks. I've gone the whole route including Radical Prostectomy and radiation in 2009. A key to survival is you need to do whatever it takes including another biopsy if needed. You might also consult with another doctor. The Mayo Clinic offers a C11-choline PET scan that can see active cancer cells with a low PSA of 2+. In other tests it would possibly need to be 20+.

@safari1949, have you any lasting side effect since surgery and radiation?

@kane59, good questions to @fairway5 about rectal MRI. Are you scheduled to have one?

Mayo wants to schedule a rectal MRI in about 4 months. My question was, is the rectal MRI as painful as the biopsy? The manuvering of the probe during the biopsy was a killer! My biopsy experience will last a life time.

I had the same torturous experience. The good news on your upcoming MRI is that if you're proactive, you can request the alternate method which does not use the "coil", I've been trying to find the right term to use when inquiring about it. The phrase started with or included "glyco or maybe gluco". My nurse said the chemical method was actually a better image than the coil method.