Gleason 6 But high decipher score.

Posted by caryg1955 @caryg1955, Jul 24 4:59pm

Treatment suggestions for newly diagnosed 69-year-old Gleason 6 In 2 out of 15 Biopsy samples. Both malignant samples were in a small nodule. Had high decipher score. PSA rose from 2.5 to 3.83 which indicated an MRI and then A fusion biopsy. Thinking of going with IMRT Radiation without ADT therapy. Please let me know your thoughts.

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@hirejohn

Hi cs2024 - Just a quick follow up. When reviewing this thread, it seemed like the majority of folks like us (low risk clinical markers with high Decipher risk), opted for surgery. Just curious why you opted for IMRT. As you mentioned, just trying to gather as much information as possible before making this rather difficult decision. Thanks again for weighing in earlier.

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My journey is similar to cs2024. Multiple consults surgery vs radiation. Had an ArteraAI test which suggested no measurable benefit by adding ADT - chose no ADT at least for now. That's an interesting story ...
MRI PI RAD 4 - 15 core biopsy 10 3+3= Gleason 6 - 5 3+4 = Gleason 7. PSMA no visible metastasizes. Diagnosis for me is UNfavorable Intermediate PC because of volume. I'm 71, PSA topped out 5.3 this year watched it for 10 years. One of my consults was with the Dept Head of Urology at Moffitt. He said flip a coin between surgery and radiation. Statistically each offered similar 10 year outcomes. I chose radiation IMRT/28 treatments with lymph nodes just in case.
The bladder prep is irritating ( I have 7 left and counting the days).
No perfect answer. We are all different.
Tech is your friend. Constant changes. Always something new.
Good luck.

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@gregblue1

My journey is similar to cs2024. Multiple consults surgery vs radiation. Had an ArteraAI test which suggested no measurable benefit by adding ADT - chose no ADT at least for now. That's an interesting story ...
MRI PI RAD 4 - 15 core biopsy 10 3+3= Gleason 6 - 5 3+4 = Gleason 7. PSMA no visible metastasizes. Diagnosis for me is UNfavorable Intermediate PC because of volume. I'm 71, PSA topped out 5.3 this year watched it for 10 years. One of my consults was with the Dept Head of Urology at Moffitt. He said flip a coin between surgery and radiation. Statistically each offered similar 10 year outcomes. I chose radiation IMRT/28 treatments with lymph nodes just in case.
The bladder prep is irritating ( I have 7 left and counting the days).
No perfect answer. We are all different.
Tech is your friend. Constant changes. Always something new.
Good luck.

Jump to this post

Thanks, gregblue1. Appreciate your input. As you noted, no perfect answer.
Good luck to you as well.

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