Gleason 3+4, How did you treat?

Posted by keithl56 @keithl56, 1 day ago

Just got my pathology report back and have a Gleason score of 3+4 (ironically on the opposite side of the targeted lesion).

I'm interested in hearing how others treated this. I know that there are a ton of variables beyond the Gleason score (age, comorbidities, quality of life concerns). In my case I'm 70 with CAD.

Thanks in advance!
Keith

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keithl56 | @keithl56 | 3 hours ago

Great feedback. I can relate since I also have had 2 knee surgeries, a cervical fusion, and 2 lumbar surgeries, last being a fusion. By far the most painful procedures and recoveries were the lumbar ones (although they had to intubate me while fully conscious for the cervical, which was not fun!). My Decipher score will definitely influence my decision as well.

ioamich | @ioamich | 5 minutes ago

Hello,
70 years old, with biopsy-confirmed CaP (3+4).
Some more information would be appreciated, such as:
PSA history and progression, Multi-Parametric MRI of the prostate report, prostatic volume, % cancer volume, PSAD, histology separately from both lobes, if any perineural invasion is identified, CT scan and bone scan results, if PSMA CT has been done and the outcome reported. Important: Performance status and comorbidities (ASA) with any treatment being received.
Potential options dependent on all above:
1. RP or 2. Hormones + Radiotherapy or 3. Active Surveillance.