Anyone on Gemcitabine with Abraxane? How long? Effective?

Posted by helenar @helenar, Aug 17, 2022

Hi, I'm Helena from South Africa. I have been diagnosed with PC, stage 4, in March. Tumour between body and tail and with one lesion on my liver.
I have been on Folfirinox for 3months, but it had no effect, allthough my markers came down from 3091 to 357, the tumour increased in size and there is another lesion on my liver.
I have started Gemcitabine with Abraxane.
Has anyone been on Gemcitabine/Abraxane?
If so, how long and how effective is this treatment?

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Profile picture for joealp1 @joealp1

@shscott
I've been on gemcitabine and abraxane, biweekly, for the past two months, 4 treatments so far. Fatigue is the biggest of my issues, maybe a little joint pain. No fever. Good luck.

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@joealp1
Thank you for your response. Fatigue and flu like symptoms have been my husbands main side effects but fever seems to follow on the 3rd or 4th day after treatment.

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Profile picture for etto @etto

Ditto. Biweekly, 4 treatments so far. Joint pain, especially in hips. Fatigue is a biggie, no fever, hair is mostly gone. I'm icing hands and feet during abraxane and so far minimal neuropathy. Generally fatigue and joint pain are better by a day into week 2 each time. CA19-9 has been steady, CT next week - we'll see if this is helping. Yes, good luck to all.

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@etto Good luck with the CT next week. Please let us know how it goes?

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Ditto. Biweekly, 4 treatments so far. Joint pain, especially in hips. Fatigue is a biggie, no fever, hair is mostly gone. I'm icing hands and feet during abraxane and so far minimal neuropathy. Generally fatigue and joint pain are better by a day into week 2 each time. CA19-9 has been steady, CT next week - we'll see if this is helping. Yes, good luck to all.

REPLY
Profile picture for joealp1 @joealp1

@shscott
I've been on gemcitabine and abraxane, biweekly, for the past two months, 4 treatments so far. Fatigue is the biggest of my issues, maybe a little joint pain. No fever. Good luck.

Jump to this post

REPLY
Profile picture for shscott @shscott

My husband has stage IV pancreatic cancer with Mets to his liver. He had four cycles of Folfirinox with progression of his cancer. He was switched to gemcitabine and abraxane. He has had three doses so far. Does anyone else get fevers for a few days after their treatment?

Jump to this post

@shscott
I've been on gemcitabine and abraxane, biweekly, for the past two months, 4 treatments so far. Fatigue is the biggest of my issues, maybe a little joint pain. No fever. Good luck.

REPLY

I have been on abraxane & gemcitabine since July 29.2022. Had a 4-month break and last week had my 81st treatment with them. Sometimes I get cold like martyp01 and bundle up then get hot but not a real fever. My CT scans every 3 months have seen the tumors in my lungs shrink as well as on my adrenal gland. I have been stable for many months but my CA19-9 rises to the 90s and falls to the low 40s. I cannot seem to get it (CA19-9) back within normal range so I could have a few months without it again. To gsterle: I have had the hair loss (it did start to return during my 4-month break. I also have neuropathy to my fingers, hands, toes & feet. Acupuncture helped some but I really started too late & now have DVTs (blood clots) in 4 places in my right leg so I am off acupuncture and on Eliquis for 3 months minimum!

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Profile picture for shscott @shscott

My husband has stage IV pancreatic cancer with Mets to his liver. He had four cycles of Folfirinox with progression of his cancer. He was switched to gemcitabine and abraxane. He has had three doses so far. Does anyone else get fevers for a few days after their treatment?

Jump to this post

@shscott Yes I was on gemcitabine and abraxane and got fevers for few days after treatment. I took Tylenol every 6 hours to help keep the fever in check. It mainly worked but I would still get cold and bundle up and that would raise my temps again, so I had to drink cool drinks and unbundle to get the temp down.

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Profile picture for shscott @shscott

My husband has stage IV pancreatic cancer with Mets to his liver. He had four cycles of Folfirinox with progression of his cancer. He was switched to gemcitabine and abraxane. He has had three doses so far. Does anyone else get fevers for a few days after their treatment?

Jump to this post

@shscott i’ve had four rounds of gem/abrax with heavy fatigue but no fever. Lost all my hair and have nerapothy fingers and toes are numb but had good CAT results 35% shrinkage liver lesions and stomach lesions

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Profile picture for ro0891 @ro0891

@shscott My father had the same treatments. The Gem/Abrax took a bit of a toll on him, much more than the Folfirinox did. He would be super weak after treatments- but I do not recall any fevers.

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@ro0891
Thank you for your response. He has been hospitalized 24 days in the past 6 weeks with fevers. His port was removed and cultured negative. The biliary stent was replaced. I’m thinking it’s the chemo causing fever but not sure.

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Profile picture for shscott @shscott

My husband has stage IV pancreatic cancer with Mets to his liver. He had four cycles of Folfirinox with progression of his cancer. He was switched to gemcitabine and abraxane. He has had three doses so far. Does anyone else get fevers for a few days after their treatment?

Jump to this post

@shscott My father had the same treatments. The Gem/Abrax took a bit of a toll on him, much more than the Folfirinox did. He would be super weak after treatments- but I do not recall any fevers.

REPLY
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