FOLFIRI cause hot anus ulcers

Posted by bakerkt @bakerkt, May 9 1:01pm

Hello All,
I'm Khaled from Saudi
Arabia. I was diagnosed with mCRC on November, 2020. On December 18, 2020, I started chemotherapy (FOLFOX) at Mayo Clinic in Rochester, MN. After 6 chemo sessions and 5 radiation sessions, I subjected to a big surgery to remove the cancer from colon and liver. After that, I continued with chemo therapy (FOLFIRI) for just one session and the remaining 5 sessions only with Fluorouracil .After that I had an MRI and the result showed that I'm NED and my body was clear of cancer. I turn back home on October then my CEA has increased up to 10. Then, in KFSHRC in Riyadh I had another MRI and CT scan and the result showed that there are around 5 tumors back to my liver .Then the consultation group decided to make another surgery. I had the surgery in May 2021. After two months of surgery, I had an MRI scan and unfortunately the tumors returned again to my liver. Then my doctor decided to get back to chemo therapy starting with 6 sessions of FOLFOX then 8 sessions of FOLFIRI out of 12 as planned.

My concern is that I strongly suffer from a very hot anus ulcers that lasted for ten days at least and prevented from sleeping for 3 days with a strong pain, it feels like embers in my bottom. Does anyone have a similar case? And what is the treatment for this case?

Thank you in advance!

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Colleen Young, Connect Director | @colleenyoung | May 23 8:25pm

@bakerkt, the ulcers sound very painful and obviously losing sleep makes healing a challenge. I'm tagging other colorectal cancer members who have experience with FOLFIRI like @colca and @barbgunter67 to see if this is a side effect they had to deal with.

Khaled, how often are your chemo treatments? Did you experience the painful ulcers this latest round?

tenpro | @tenpro | May 24 6:13am

In reply to @colleenyoung "@bakerkt, the ulcers sound very painful and obviously losing sleep makes healing a challenge. I'm tagging..." + (show)

Since I began infusion and pump I've had diarrhea and anus inflammation, very sore, hard to sit and. many times. standing.

I've been trying baby rash cream seems to assist in calming down.

bakerkt | @bakerkt | May 24 8:03am

In reply to @colleenyoung "@bakerkt, the ulcers sound very painful and obviously losing sleep makes healing a challenge. I'm tagging..." + (show)

Thank you, Young,
Acutely, my treatment plan is to have chemo every two weeks, and I was experienced this painful since the first FOXFIRE (I had Eight sessions so far and six Fol fox earlier)session but was not last for more than Four days and got worst with next chemo.
FYI, I had PET Scan last week and It's showed an inflammation along the whole colon canal and I have appointment next week with colon and rectum specialist doctor for his advice.

Thank you again, Young for your help.