Ezetimibe and Neuropathy

Posted by tprift @tprift, 4 days ago

I was prescribed Ezetimibe in place of a statin for high cholesterol. I declined to use a statin because of my peripheral neuropathy.
Anyone have experience with this drug?

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Just a quick follow up. I was also hesitant to add the Esztimibe. Cardiologist said this med has shown itself to help lower stubborn cholesterol that seems stuck in going down. He was Right!!!! Numbers really went down. (Only taking 10MG).

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@celia16

I get it. I suppose this med helped me much more than it does most. With just 10 mg of it, I went from cholesterol of high 190s to 140s..and this was with bad diet and obesity. I then lost a lot of weight, changed diet and exercised. Switched to statin (low dose) and cholesterol went up slightly. Sigh. So, thinking of adding Zetia back.

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Hello, my cardiologist has taken me off the rosuvastatin as I was taking once a day. I am also taking fish oil once a day of which I take twice a day now. Neither one of the drugs had an effect on my PN.

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@julbpat

I have been on it for at least 15 years. No side effects.

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Did it lower LDL much?

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@celia16

I get it. I suppose this med helped me much more than it does most. With just 10 mg of it, I went from cholesterol of high 190s to 140s..and this was with bad diet and obesity. I then lost a lot of weight, changed diet and exercised. Switched to statin (low dose) and cholesterol went up slightly. Sigh. So, thinking of adding Zetia back.

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Adding Zetia to my REPATHA brought my LDL-C way down. I couldn't take statins.

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So, in light of my previous good results and others’ good track record…..why did my PC tell not to take Zetia AND my low dose statin? AND my endocrinologist said it probably wouldn’t matter! What? What am I missing? Next month I’m going to take this up with my current endocrinologist.

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@celia16

So, in light of my previous good results and others’ good track record…..why did my PC tell not to take Zetia AND my low dose statin? AND my endocrinologist said it probably wouldn’t matter! What? What am I missing? Next month I’m going to take this up with my current endocrinologist.

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I don't think Primary Care Dr will be up to date on latest developments in cholesterol medication and which one is most indicated in certain situations.
Many years ago, I was prescribed Atorvastatin (Lipitor) by my Primary Care doctor. Then 3+ years ago they discovered a 70% blockage in LAD. While waiting for a stent, a Nurse in local Cardiology dept doubled my Atorvastatin (to the max dosage) to lower my LDL to under 70. It had no effect - my cholesterol stayed at 95 when they want it below 70! I then saw a cardiologist and he instead prescribed Rosuvastatin (Crestor) with Ezetimibe. That immediately lowered my cholesterol to under 70! I have had no side effects.

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