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Exodx test
Recently I had an mri for an psa of 5, they found an .8 cm wedge lesion and said fi di gs consistent with prostatitis and gave it a pirads 4 rating. He wanted to do a exodx test to determine whether to proceed to a biopsy. What scores are worrisome and how accurate are they in predicting aggressive cancers. Say if you get a 30 score does that mean higher probability of higher Gleason score than 7.
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Definitely go ahead with either the ExoDx urine test or PSE blood test. I understand the PSE has a higher accuracy percentage, but regardless you could always start with the one your Urologist us first recommending or ask him about the other. The ExoDx assesses your risk of having a clinically significant high grade prostate cancer. My PSA was low but started fluctuating, still at a low number and the MRI listed what appeared as possibly prior prostatitis scarring and so we just continued to take quarterly PSA tests for a year, before deciding to get the ExoDx. It was 72, so about 15 months after my last MRI went back in for another and this time they identified the lesion, likely more prominent now as a PIRADS 4, so definitely moved on to biopsy, but the PIRADS turned out benign, but found cancer in other cores including one 8 (4+4) later downgraded after surgery to a 7 (4+3)
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1 ReactionDid have to go on adt therapy or can you avoid that with a 4+3 score.
Can you avoid adt therapy for a 3+4 Gleason score?
@ginger38314
I did not need ADT after my single port Retzius sparing RALP. I am currently 18 months post surgery on 6 month PSA tests now with all of them <.04 undetectable.
I also had cribriform pattern identified, but not whether large or small
@ginger38314
You can avoid ADT therapy under that condition. But the Gleason score alone is not enough to make that decision.
You do not mention having a biopsy. Did you have one?
Were any of these things found in the biopsy intraductal, ductal, large cribriform, Seminal vesicle invasion, EPE or ECE. (Extraprostatic extensions extra capsular extensions). They can make the cancer much more aggressive. If you have some of these, you may need ADT.
Here is a list of the tests people take to decide whether or not they have prostate cancer and need a biopsy. You will notice that the PSE test has much higher accuracy, The ExoDx, not so much.
That's fantastic, I'm hoping for a low exods score to avoid the biopsy my
psa is currently at 5 and a density of .16 and the lesion is wedge shaped
and .8cm but in the summary they noted findings consistent with prostatitis
but gave it a pirads 4.
How long did it take you to recover from your surgery?
@ginger38314
I would say two weeks. I was walking a mile with my catheter in three days later. I had the catheter in for 11 days due to a holiday weekend and felt comfortable to drive with it in, but my wife would not let me. Once it was out I was out and driving. Now when I say two weeks, I was not doing physical activities like jogging or lifting anything heavy. At three weeks I was in the car for a two hour drive. I can say within a month the surgery was history, off flying international. My single port scar cannot even be seen now.
No they did a exo ds test yesterday because the mri showed an infection tpp.