evolution of treatment over time

I was diagnosed with PV JAK2 a year ago and have taken HU for six weeks, then had bone marrow biopsy that shows TET2 and AXL1. Was put on Ruxolitinib because the HU was causing problems with the good blood cells. On Ruxo (Jakafi) for six weeks and my platelets took a nosedive along with whites diminishing more so than with HU.
Now I do monthly phlebotomies unless the blood test numbers don't support one and then usually have one two weeks later.
My question is: at 74 I'm concerned with stroke and heart attack with no medication. I exercise, eat well, don't drink and live at 6800 feet. Can I expect to stay on this track for some time to come?