Anyone taken Evenity (romosozumab) for Osteoporosis?

Thxs @windyshores, I wanted to ask you this question earlier, then lost my page, lol. Why they both were against you trying Evenity, for a maybe short time, after tymlos.

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Sorry for the delay in response but I did call Amgen twice since my post. The first person I spoke to about the possibility of Evenity containing sulfa basically said Evenity has never been tested for the presence of sulfonamides. She also said the raw materials used in the inactive ingredients in Evenity could vary according to availability. Sulfa is not listed as an ingredient in Evenity. That is the short answer. She never gave me a yes or no answer so after a few days I decided to call again.
This time I spoke to a pharmacist who read all of the ingredients to me and gave a similar but more detailed answer. He said the active ingredient in Evenity is a protein which is not expected to contain sulfa. There are also several inactive ingredients in Evenity. Due to the raw materials used to make the inactive ingredients there could be trace amounts of sulfonamides present. He emphasized “trace amounts” depending upon the raw materials used. My understanding of this is there could be trace amounts of sulfonamides present in Evenity depending upon which raw materials were used. He advised me to discuss this with my doctor. I can only assume this can happen with other drugs as well. I see my rheumatologist tomorrow to make the big decision.
I had been on Prolia for 3 years and had a total of 6 injections. I also had 4 compression fractures while on Prolia which I let heal naturally. I stopped Prolia after the 6th shot so I could have minor dental surgery. I had another compression fracture almost immediately and this time it was much worse. I was referred to a neurosurgeon and I had 4 kyphoplasties performed to fix the fractures. I was told to suspend the Prolia by my surgeon until after my procedure. While recovering from surgery I had 4 more compression fractures probably due to stopping Prolia but I had no choice in the matter. I had 4 more kyphoplasties to repair the new fractures and now it’s time to get back on something for my osteoporosis.
I reported all of this to Amgen and the pharmacist suggested that maybe Prolia wasn’t the best choice for me. I was told by my rheumatologist that since I had brachytherapy radiation for breast cancer 8 years ago I could not take Forteo or Tymlos. Evenity is probably my best option right now but is a really hard decision to make.
I have been told by 2 doctors that the Letrozole I took for 5 years for my bout of breast cancer most likely caused my osteoporosis. My surgeon said that the spine does not respond to osteoporosis drugs as well as other bones in your body when chemo meds are the main cause of your osteoporosis. I feel like I’m caught between a rock and a hard place but I have to do something before things get worse.

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Hello all,
I have osteoporosis, am on Letrozole and am worried about exacerbating it with this hormone blocker. My nutritionist had me switch my calcium pills to Algecal Plus and I also take Strontium booster. I also had my vitamin D checked and it was 21. It's now up to 43, but she wants it over 50. So, I'm getting there. It's really important to make sure your vitamin D is high enough for your bones to absorb the calcium. I also started a program at Osteostrong which will help build your bone. If you check out the NIH medical library website, you can see these really do work. I'm very hopeful.

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I posted a separate discussion on Evenity after Tymlos (or after Forteo). I have gotten two opinions and neither will prescribe that sequence due to "lack of data" so I am curious how/where people are getting this prescribed.

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"No data," "being studied." I am frustrated. I respect their caution but a lot of people on this forum are doing Evenity after Tymlos and with 7 fractures and a femur neck still at -3.6, I need more bone growth before "locking in."

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Hello all,
I have osteoporosis, am on Letrozole and am worried about exacerbating it with this hormone blocker. My nutritionist had me switch my calcium pills to Algecal Plus and I also take Strontium booster. I also had my vitamin D checked and it was 21. It's now up to 43, but she wants it over 50. So, I'm getting there. It's really important to make sure your vitamin D is high enough for your bones to absorb the calcium. I also started a program at Osteostrong which will help build your bone. If you check out the NIH medical library website, you can see these really do work. I'm very hopeful.

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Yes, I'm really sorry to hear that outcome @windyshores. If they said it was counterproductive, ineffective, or *harmful in that sequence, I'd understand. We really have to be our own advocate, too much has happened where the medical community has been asleep.

Thx for all your info, much appreciated.

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@windyshores, I can see you are your own advocate by all your research. Evenity seems to be so great at building bone before a bs, I guess I was hoping to be able to build as much as possible before thinking bs. I was hoping for you too! Take care.

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