Epidermal Nerve Fiber Density Test
I have had a skin punch biopsy twice, 13 years apart. The second test showed a roughly 33% loss of small nerve fibers at calf and thigh. My neuro reacted by saying my results are consistent with the new medical understanding that SFN is always non-length dependent. Good learning. But my question to this group is this: Has anyone’s subsequent punch biopsy shown an increase in ENFD? My neuro said the small nerve fibers are capable of regeneration and because I am pre-diabetic to concentrate on weight loss, diet and exercise to help recovery. I have had SFN since 2006 but it presented as Benign Fasciculation & Cramp Syndrome.