Energy Improvements After Resuming Testosterone Replacement Therapy?
For men who began receiving Testosterone Replacement Therapy (TRT) after successfully completing PCa treatment, how long did it take for post-ADT energy improvements to become noticeable?
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It was immediate. My testosterone levels rose and my blood values normalized . We began reducing added testosterone until blood levels dropped to 100 or so. When we stopped with testosterone injections, but testosterone dropped back to zero, but my blood values remained barely in range on the low side.
I wonder if the purpose of ADT is to compromise the body's capacity to produce testosterone in 'normal' amounts ever. For a person my age (74) it would kind of make sense, except for the concerns that I have about muscle loss. I would like to know if there is a way of significantly slowing muscle loss. I've seen some things on YouTube, that I've since lost track of, that involved taking supplements. Does anyone have any knowledge on this question.
As much as I hate ADT and initially resented how it was presented by PC YouTube education websites, I learned through experience that it has a profound beneficial impact on treating PC.
I'll address only one part of ADT -- i.e., the one that I experienced for purposes of making PC radiation treatments more effective.
When I received my Gleason 4+3 unfavorable intermediate cancer diagnosis I reluctantly decided to immediately stop my TRT. I had read and seen the statistics that PC recurrences for Gleason 4+3 were about 50% better by eliminating testosterone before starting radiation treatments. Here's what happened to me:
Day #1: Total testosterone (TT) = 950 and PSA = 8.1
Day #15: TT = 350; PSA = ??? (PSA not tested at that time)
Day #30 TT = 51; = PSA 1.9
Day #60 TT = 48; PSA = 1.2; this was the last day before starting my SBRT radiation treatments
Day #90 TT= 50; PSA = 0.10
Day #180 TT = 22; PSA = 0.11
What did I learn? Removing testosterone prior to starting radiation weakens PC and makes it more capable of being destroyed by the radiation. Radiation oncologists label the use of ADT in this context as a "radiosensitizer".
Of course ADT has other uses in treating PC. For my situation, however, the ability of ADT to function as a radiosensitizer and improve the effectiveness of the radiation treatments made it worthwhile to endure for a six-month period.
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