With my first Zoladex injection my legs got hot and my body got covered in a really itchy rash.
I also have heavy fatigue and can’t walk near as much as before. I also get a bit of depression from it.
I am 74 years of age.
Anyone else get similar side effects
Hi Ben,
Exactly the same for me it is an evil drug
I had my first injection 8th July 2020 and it lowered my PSA After a few injections it was obvious that it was causing me massive itching/burning problems all over my body but really bad on my legs. My Dr kept saying that he doubted it was caused by the Zoladex. I went 18 months without it till my PSA started rising again and my Dr talked me into having another injection. I had that with no real problems but shortly after the second injection 3 months later the itching/burning has returned. I told my Dr last week I will never have another one I would prefer the cancer. Never again for me
Ben, you might ask before your appointment if there is something you can take or they can give you before the injection to reduce the allergic effect. It's worth asking about.
Colleen if the rash comes back with this shot I will talk to my oncologist to see if there’s something he can prescribe to stop it. I have an appointment in April so I will find out then.
When I reported to my oncologist he was quite surprised that my rash was so bad, he expected some rash but not like I had. He also wasn’t surprised by my legs getting hit but that only lasted fo a few hours.
For my rash I used Cavilon barrier cream made by the 3M company. When I started using that the itching went away in a very short time and in a few days my rash was almost all gone. I had to order it on Amazon since no stores around here carry it.
I am getting another shot tomorrow so I will see how the reaction goes then.
Ben, you might ask before your appointment if there is something you can take or they can give you before the injection to reduce the allergic effect. It's worth asking about.
Ben, the legs getting hot and the itchy rash sound like it might be an allergic reaction. Did you report your symptoms to your oncologist or symptom management nurse?
When I reported to my oncologist he was quite surprised that my rash was so bad, he expected some rash but not like I had. He also wasn’t surprised by my legs getting hit but that only lasted fo a few hours.
For my rash I used Cavilon barrier cream made by the 3M company. When I started using that the itching went away in a very short time and in a few days my rash was almost all gone. I had to order it on Amazon since no stores around here carry it.
I am getting another shot tomorrow so I will see how the reaction goes then.
I don’t know whether it was due to Zoladex or Abiraterone, but lots of intermittent hot flashes, energy levels lower than before. After 4 months now, it’s better. But actually the fatigue factor got immensely worse after my Tomotherapy.
With my first Zoladex injection my legs got hot and my body got covered in a really itchy rash.
I also have heavy fatigue and can’t walk near as much as before. I also get a bit of depression from it.
I am 74 years of age.
Anyone else get similar side effects
Ben, the legs getting hot and the itchy rash sound like it might be an allergic reaction. Did you report your symptoms to your oncologist or symptom management nurse?
With my first Zoladex injection my legs got hot and my body got covered in a really itchy rash.
I also have heavy fatigue and can’t walk near as much as before. I also get a bit of depression from it.
I am 74 years of age.
Anyone else get similar side effects
After radiation in 2017 on Zolodex for 2 years Zero issues PSA <.01 odd sweat
Taken off three year later metastatic castrate sensitive in spine Nuked L2 lumbar 1 inch cancer then back on Zolodex PSA 1.2 for 2 years Rose to 4,22 last week but done at different lab
Getting retested Stay on Zolodex 3 month injection Testosterone Is the e fertilizer of PC
Neil..I was on Zoladex (pill) prior to and for about a month after radiation. The shot option wasn’t even offered. I experienced, weakness, bouts of tiredness and just a general feeling of the blahs. All these side effects subsided over time ( about 6 months or so). It’s been 2 1/2 years since the treatment, and the effects are a distant memory. In my opinion, the effects of Zoladex, were well worth the benefit it provides in the treatment of prostrate cancer. Best of luck with your journey. Take care. Reach out to your providers if needed. My experience with the Mayo personnel has been outstanding.
Neil…After review of my Zoladex treatment, I was given 2 Injections (not pills as previously mentioned by me, guess I got this mixed up with other meds I was taking).
Sorry for the confusion.
Take care
Neil..I was on Zoladex (pill) prior to and for about a month after radiation. The shot option wasn’t even offered. I experienced, weakness, bouts of tiredness and just a general feeling of the blahs. All these side effects subsided over time ( about 6 months or so). It’s been 2 1/2 years since the treatment, and the effects are a distant memory. In my opinion, the effects of Zoladex, were well worth the benefit it provides in the treatment of prostrate cancer. Best of luck with your journey. Take care. Reach out to your providers if needed. My experience with the Mayo personnel has been outstanding.
Connect
Connect
Like
Helpful
Hug
Hi Ben,
Exactly the same for me it is an evil drug
I had my first injection 8th July 2020 and it lowered my PSA After a few injections it was obvious that it was causing me massive itching/burning problems all over my body but really bad on my legs. My Dr kept saying that he doubted it was caused by the Zoladex. I went 18 months without it till my PSA started rising again and my Dr talked me into having another injection. I had that with no real problems but shortly after the second injection 3 months later the itching/burning has returned. I told my Dr last week I will never have another one I would prefer the cancer. Never again for me
Colleen if the rash comes back with this shot I will talk to my oncologist to see if there’s something he can prescribe to stop it. I have an appointment in April so I will find out then.
Ben, you might ask before your appointment if there is something you can take or they can give you before the injection to reduce the allergic effect. It's worth asking about.
When I reported to my oncologist he was quite surprised that my rash was so bad, he expected some rash but not like I had. He also wasn’t surprised by my legs getting hit but that only lasted fo a few hours.
For my rash I used Cavilon barrier cream made by the 3M company. When I started using that the itching went away in a very short time and in a few days my rash was almost all gone. I had to order it on Amazon since no stores around here carry it.
I am getting another shot tomorrow so I will see how the reaction goes then.
I don’t know whether it was due to Zoladex or Abiraterone, but lots of intermittent hot flashes, energy levels lower than before. After 4 months now, it’s better. But actually the fatigue factor got immensely worse after my Tomotherapy.
Hi @ben789, I moved your question about side effects from Zoladex such as rash, depression and fatigue to this existing discussion:
- Effects of Zoladex: https://connect.mayoclinic.org/discussion/effects-of-zoladex/
I did this so you can read the previous posts and connect with other members like @bodeygolfer @jap57 @tassieb @neil27 and @melcanada.
Ben, the legs getting hot and the itchy rash sound like it might be an allergic reaction. Did you report your symptoms to your oncologist or symptom management nurse?
-
Like -
Helpful -
Hug
1 ReactionWith my first Zoladex injection my legs got hot and my body got covered in a really itchy rash.
I also have heavy fatigue and can’t walk near as much as before. I also get a bit of depression from it.
I am 74 years of age.
Anyone else get similar side effects
After radiation in 2017 on Zolodex for 2 years Zero issues PSA <.01 odd sweat
Taken off three year later metastatic castrate sensitive in spine Nuked L2 lumbar 1 inch cancer then back on Zolodex PSA 1.2 for 2 years Rose to 4,22 last week but done at different lab
Getting retested Stay on Zolodex 3 month injection Testosterone Is the e fertilizer of PC
Neil…After review of my Zoladex treatment, I was given 2 Injections (not pills as previously mentioned by me, guess I got this mixed up with other meds I was taking).
Sorry for the confusion.
Take care
Neil..I was on Zoladex (pill) prior to and for about a month after radiation. The shot option wasn’t even offered. I experienced, weakness, bouts of tiredness and just a general feeling of the blahs. All these side effects subsided over time ( about 6 months or so). It’s been 2 1/2 years since the treatment, and the effects are a distant memory. In my opinion, the effects of Zoladex, were well worth the benefit it provides in the treatment of prostrate cancer. Best of luck with your journey. Take care. Reach out to your providers if needed. My experience with the Mayo personnel has been outstanding.