Looking for info on HDR Brachytherapy to ask Radiation Oncologist

Posted by robertov @robertov, May 24 1:37pm

I’m trying to decide on IMRT, Proton Therapy 5 fractions, or HDR for localized Gleason 4+4 PC. PSMA came back clean. I keep wavering. Looking for a good HDR site and discussion with RO about it.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

@robertov

Thanks Jeff. I was wondering If there were any differences between 5 fractions vs 45 fractions. I’ve read the studies showing no diffs. Not sure whether i trust them.

Jump to this post

I’m sorry, but I have no firsthand information about this.

REPLY
@robertov

Thanks Phil. What i meant was no cells were removed to send for a decipher test. I assume you need the actual cells? I just assumed all that was left were pictures. I think you are suggesting the ‘slides’ can still be used for a decipher test?

Jump to this post

Yes, I am. I remember reading about it somewhere; but your urologist really did you no favors by neglecting this test. With all I’ve learned about the shortcomings of PSMA scans, I put greater trust in the odds offered by genetic testing.

REPLY
@robertov

You are exactly right. My RO wants to treat the pelvic nodes. You bring up a distinction that i have missed: whether SBRT or Proton therapy can do the pelvic nodes. Now I’m not sure.

Jump to this post

I am fairly certain all the different modalities can work; it all comes down to user preference and confidence in what they know best.
45 treatments does seem a bit old fashioned these days, but if this dr has great success with it, I would say to let him do his thing. But you should ask Dr Proton if he’s treating the nodes as well during his 5 sessions.

REPLY

There is no such thing as a cure. Going into long-term remission is more like it.

If the doctor doing IMRT isn’t doing anything more than the prostate itself. I would not really think that It would be any better than the SBRT sessions. You say he is also going to treat the pelvic lymph nodes, still not an issue.

At the latest PCRI conference on March 29 a doctor was saying that the reason doctors are doing IMRT is because they make more money doing it than they make doing SBRT. Those extra sessions really add up financially, but they don’t really give you any extra benefit. They can do SBRT to the prostate and the lymph nodes in many fewer sessions.

REPLY
@robertov

That is so weird that 5 years later it would occur. What is your understanding of why that happens.

Jump to this post

If you look it up, you will find there are a number of things that happened after five or 10 years from the time radiation is given. Incontinence is only one of the problems..

REPLY

I dealt with 3 top institutions and all had their procedures and protocols. Mayo emphasizes proton radiation that is a leading and relatively new methodology where they've invested a tremendous amount of resource in the machines that a number of other institutions do not have. I certainly considered treatment at Mayo for this reason, but, decided I could get similar results here in California with the other two major institutions that I was working with, both of whom had their own procedures and protocols that differed widely. The challenge is being able to determine what is best when the providers are not objective.

I was treated two years back as a 71 Year old male with NCCN unfavorable intermediate risk prostate adenocarcinoma -- T1c (T3a based on MRI) M0N0 ISUP Group Grade 3 (Gleason score 4+3; 4/14 systematic cores); initial PSA of 4.08 ng/mL; Decipher 0.57 intermediate. PET scan: negative.

After a great deal of discussion and research, I completed tri-modal: Orgovyx/4 months; 2x Cyberknife boost; 23x IMRT and now, thankfully, am in "remission". However, I was days away from having HDR Brachytherapy as boost radiation. What changed was that I met a friend who is a retired urologist and current CMO of a medical group. We were able to talk 'off the record' and he told me that two of his close friends had damaged rectums from HDRB, and while he fully supports that institution, he suggested that I look into alternatives. I was able to find another RO who had moved away from HDRB to Cyberknife as boost radiation and published several papers on the topic, one of which I have attached. Of course, avoiding general anesthesia and a catheter had an effect on my decision as well.

Best of luck choosing the right treatment for your case. MCC has been my other independent advisor and I am grateful to have all these wonderful sources of information!

Shared files

chen_roach (chen_roach.pdf)

REPLY
@jeffmarc

There is no such thing as a cure. Going into long-term remission is more like it.

If the doctor doing IMRT isn’t doing anything more than the prostate itself. I would not really think that It would be any better than the SBRT sessions. You say he is also going to treat the pelvic lymph nodes, still not an issue.

At the latest PCRI conference on March 29 a doctor was saying that the reason doctors are doing IMRT is because they make more money doing it than they make doing SBRT. Those extra sessions really add up financially, but they don’t really give you any extra benefit. They can do SBRT to the prostate and the lymph nodes in many fewer sessions.

Jump to this post

Yes, I read that many times. Canada which doesn’t have the profit motive AND collects more and better data due to the centralized public health considers SBRT just as effective and have data to back it up. Thanks Jeff!

REPLY
Please sign in or register to post a reply.