Does anyone take agomelatine for their anxiety and depression?

I had never heard of diurnal mood variation, but it sounds what I've been dealing with for over three years. Horrible anxiety and dread that starts even before I'm fully awake, but usually becomes mure manageable as the day goes on. By evening I often feel fairly normal, and go to bed hopeful that the morning horrors won't come back.But they always do, to a greater or lesser extent.
I have resisted meds, but seeing that you've gotten at least partial relief, I should probably reconsider. Waking up every day in fear of my own life is,well, no way to live...

It appears as though in reading available literature on Agomelatine that it was not approved in the US as Phase 3 of the clinical study indicated that it could cause liver damage. Not sure which Pharmaceutical company is doing the Clinical Trails/Research

Thank you so much for replying and for providing helpful information. Much appreciated!!!

Hi! Thank you for your reply. It does sound like you may have diurnal mood variation but your health care provider would know best. Like you, I go to bed hopeful that I won’t have that horrible feeling of dread and anxiety. Please consult your doctor so you don’t have to suffer. Take care and keep me posted, if you feel like sharing.

If it helps, I,too, awaken horribly frightened and feel I cannot face another day and then I am better at night. This is truly horrible to deal with day after day.

Hi! Thank you so much for your reply. I’m SO very sorry you experience the same thing that I do. However, it does help somewhat to know that we’re not alone. Have you seen your primary care doctor or a psychiatrist about it?
For many years, I took Zoloft for anxiety and depression and it really helped get rid of the morning fear and anxiety. However, the medication stopped working and now my psychiatrist and I are trying to find a new medicine that works. I’m also seeing a psychologist for cognitive behavioral therapy.
Please consider seeing a health care provider. There are lots of medications and therapy available.
In the meantime, I’m sending you hugs. Feel free to reach out to this community whenever you need to “talk”. There are some very kind and encouraging people here.

Hi across the very big pond
It's very hot in Beerwah 4519 Qld
IAM sorry for your mental health.
IAM not sure what is worse; extreme anxiety or pain.lve just started 2days agomelatine 25 mg .
Surprised it was available in Australia before you guys.Taking it morning as at night l Mirtazapine.
This all for fibromyalgia anxiety which at times couldn't go out,but do feel better in the evening. I find anxiety worse afternoon especially if lve had a small sleep...so try not sleep. You're anxiety title is different to mine,but found so much overlaps and the most common medicine seems to be the least effective. Anxiety manifests itself so so many ways even pain spasticity eating sleeping the list is endless and everyone is different. USA are definitely on the whole leaps ahead on mental health, Australia pretty good,UK getting there. But common sense should float to the top with family and friends who on the whole have no idea as if they are frightened to catch it. I tell them that absolutely everything is passed through the brain more than our bowel.
Even a sore toe. So psychiatry is definitely the largest part of medicine and l think we will soon have all sorts of psychiatry 100 s
I had one .. just ADHD Dex helped my fibromyalgia but Psychiatrist didn't go there.. unfortunately like alot of medicine our brain remaps and tabs become useless.
One good thing to do is departmentalize . I guess you've tried so many things for your condition. I find off.. label drugs help in combo with other tools in one's belt. My Sister advanced practitioner nurse tells me gin would help..so l did. It helps better than valium.. obviously no more than two gin and tonics in a row.
My doctor is amazed that it helps pain. Probably because it relaxes maybe. Because like yourself difficult medical conditions need experimental techniques. IAM aloud by GP and neurologist and psychiatrist to drink a litre of gin a week. It's safe on liver... being a white spirit and also the distillation process with juniper and other botanicals which are anti inflammatory negate the alcohol.
Anyhow it's luck to a degree,as so many things to try.
I've just started ashwaganda as a natural pre. Anxiety helper.. l haven't noticed much in the last month.
I was fortunate enough to afford 1 appointment with psychiatrist who was a neurologist aswell (top of the food chain) To me,it seems logical to head this way if one can afford it.
They definitely would have the best understanding of your condition.
Hope the hand of fate treats you well in the New year.
The very small things added together are so wonderful,but most don't stop to smell the roses.
Good book to read which might help.Sycho Cybernetics...read it when l was 18. God's Duty by Alan Ansic (not religious or backed by any church l can see.)
We are certainly fortunate to live in the 5 wise virgins (tribes/Israel) parable from Matthew. Those tribes as prophecy said. Would go to the appointed place for protection and to be a fruitful land.
Started in UK ..then it's branches went to the 4 corners of earth.
USA Canada Australia New Zealand
Best real estate on earth and most powerful combination of countries united in free will justice etc and language.
Google 5 eyes
I leave with a quote from John Lennon.
IN THE END EVERYTHING WILL BE FINE.....IF ITS NOT:THEN IT'S NOT THE END.
🌞🌛💫
God said if these 3 things (above)
Are still to be seen...then is promises to the world (prophecy, scripture) are in play.