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Does anyone take agomelatine for their anxiety and depression?
I suffer from diurnal mood variation. Agomelatine has been approved to treat it in Europe and Australia. Has anyone in the US been able to get it? Or does anyone have any information about when it might get approved in the U.S. I am terribly depressed and anxious in the morning and throughout the day. It doesn’t get better until the evening — then I start to feel “normal”. I have tried several SNRIs, SSRIs, and now I’m on Mirtazapine but have only received a partial response. My psychiatrist has recently added Lamictal but I haven’t been on it long enough to know if it will be effective. In the meantime, because I so desperately want relief from my anxiety and depression, I want to find out if anyone has taken Agomelatine?
Thanks so much! I look forward to your replies.
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I had never heard of diurnal mood variation, but it sounds what I've been dealing with for over three years. Horrible anxiety and dread that starts even before I'm fully awake, but usually becomes mure manageable as the day goes on. By evening I often feel fairly normal, and go to bed hopeful that the morning horrors won't come back.But they always do, to a greater or lesser extent.
I have resisted meds, but seeing that you've gotten at least partial relief, I should probably reconsider. Waking up every day in fear of my own life is,well, no way to live...
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1 ReactionIt appears as though in reading available literature on Agomelatine that it was not approved in the US as Phase 3 of the clinical study indicated that it could cause liver damage. Not sure which Pharmaceutical company is doing the Clinical Trails/Research
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1 ReactionThank you so much for replying and for providing helpful information. Much appreciated!!!
Hi! Thank you for your reply. It does sound like you may have diurnal mood variation but your health care provider would know best. Like you, I go to bed hopeful that I won’t have that horrible feeling of dread and anxiety. Please consult your doctor so you don’t have to suffer. Take care and keep me posted, if you feel like sharing.
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2 ReactionsIf it helps, I,too, awaken horribly frightened and feel I cannot face another day and then I am better at night. This is truly horrible to deal with day after day.
Hi! Thank you so much for your reply. I’m SO very sorry you experience the same thing that I do. However, it does help somewhat to know that we’re not alone. Have you seen your primary care doctor or a psychiatrist about it?
For many years, I took Zoloft for anxiety and depression and it really helped get rid of the morning fear and anxiety. However, the medication stopped working and now my psychiatrist and I are trying to find a new medicine that works. I’m also seeing a psychologist for cognitive behavioral therapy.
Please consider seeing a health care provider. There are lots of medications and therapy available.
In the meantime, I’m sending you hugs. Feel free to reach out to this community whenever you need to “talk”. There are some very kind and encouraging people here.