Do petite women get over-diagnosed with osteoporosis?

Posted by mmilich @mmilich, May 12 4:42pm

I came across some articles about petite women getting overdiagnosed with osteoporosis due to limitations on DEXA scans. The same article mentioned that taller women with larger bones also get underdiagnosed because the machine thinks they have more bone mass. Has anyone else heard about this, and do your doctors address this discrepancy?

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I wonder the same thing! I wonder if there is any study on that….

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Profile picture for gracierose @gracierose

I wonder the same thing! I wonder if there is any study on that….

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@gracierose I read that the medical community has known about this discrepancy for years, but they won't say anything. It allows the pharmaceutical companies to sell more of their product when they overdiagnose.

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Profile picture for lindamaegirl @lindamaegirl

@kfhoz Rems in Massachusetts only does one hip. NOTE: take a look at who the major shareholders of Dexa scare are.....surprise surprise the pharmaceutical companies that sell some of the drugs for osteoporosis!!!!

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@lindamaegirl I could be wrong but i think Dexa only does one hip.....and non dominant forearm. By the way i need to say if anyone reads my negative comments on Dexa and the pharmaceutical companies. I am never saying do not take the drugs. Each one of us has to make their own choice. All I am suggesting is that take as much time doing research on osteoporosis or any disease or drug or test as you would if you were buying a car and don't be part of a flock of sheep and just do what you are told. ASK QUESTIONS. Now with that said I will end with a chuckle: I had the same PCP for 30 years and one day as I finished my physical he in no uncertain terms told me not to come back!!!!! I was always polite, never pushy but I asked a lot of questions and ended up doing research on a drug or test he suggested and did not always do what he said. The funny thing is we got along well. They do NOT like it when you question authority! ITS Your body and not one cares more for it than YOU.

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Profile picture for gently @gently

@lindamaegirl, I'd rather rely on bone markers.
You are right about Dexa numbers getting skewed by arthritis. But the skew often raises the scores of arthritic patients because it includes the calcium of osteophytes. Scores are lower in patients with RA because inflammatory arthritis does destroy bone.
REMS may turn out to be a better instrument, but I wish the company would pay out for the clinical trials and get recovery from insurance coverage rather than financing at the expense of osteoporosis patients.

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@I think you will not see REMS covered because the pharmaceutical companies are not going to let go of the product they have large shares in DEXA!!! and who has more power than big pharma?

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Profile picture for jiitar @jiitar

@gravity3 I like Osteo Boston too, Shelly, the lady running it is great! She gets good presenters too.

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@jiitar Thanks i will look into it

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Profile picture for lindamaegirl @lindamaegirl

@I think you will not see REMS covered because the pharmaceutical companies are not going to let go of the product they have large shares in DEXA!!! and who has more power than big pharma?

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@lindamaegirl

Have you any links that would discuss any big pharma dexa connection?

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Profile picture for lindamaegirl @lindamaegirl

@I think you will not see REMS covered because the pharmaceutical companies are not going to let go of the product they have large shares in DEXA!!! and who has more power than big pharma?

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@lindamaegirl, you may be right.
But pharmaceutical companies can't prevent REMs from conducting clinical trials. Successful clinical trials are the only thing preventing REMS from FDA approval.
Rems accuracy has some of the same vulnerabilities as dexa and some that dexa doesn't have.
Rems sometimes appears to register a higher bone density than dexa, but the scores can't be compared to each other.
Dexa uses x-ray: Rems, ultrasound Dexa has a standardized algorithm, Rems, proprietary. The T score gradations that we use with dexa (with all of its problems) can't be accurately used with rems. Rems even uses a different reference population base.
Scoliosis, prior fractures in the spine, osteophytes can distort the ultrasound signal can give a inaccurate readings, (though not always) usually higher.
Rems fragility and dexa TBS seem to perform in agreement, so equally in a recent study. https://pubmed.ncbi.nlm.nih.gov/39945614/
With both test having a skilled technician improves accuracy.
Rems may prove far better than dexa. Rems can recognize small changes in bone structure earlier than dexa. Rems' best use is in comparing rems to rems.

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