Constipation from meds

I have chronic nerve pain from a couple of failed back surgeries. I have been on Lyrica, Cymbalta and most recently Effexor. It seems that when I get to a therapeutic dose, I get severe constipation. I have tried Metamucil with Colace, and Miralax without success. Seems the only thing that works is s stimulating laxative which I know isn’t good to use long term. Since this is such a common side effect of these meds, has anyone had any success getting around this? These meds really help me so I hate to give up on them. Thank you for any advice!