CLL Zanobrutinib

Started therapy for CLL after 2.5 years of wait and watch with my excellent doctor at Mayo and local haematologist.This was predicted based on prognostic factors of age(77 now) IGHV unmutated and size of lymph nodes by CT scan . 5 out of 10.No TP 53 disruption
Until that time many background tests done including FISH, CT CBC weight loss etc
Before starting therapy had CT scan, bone marrow sampling,skin check, EKG etc
Doctor gave me a choice of Brukinsa( Zanobrutinib) or combination of Venetoclax plus obinutuzumab both being equally effective in my case.l chose the capsule therapy vs Infusions for convenience.
The doctor stated me at the half dose of Zanobrutinib ( Brukinsa ) 80 mg twice a day two weeks ago.
So far no side effects. Taking allopurinol and acyclovir also.
In two weeks my WBC has gone up from about 90 to 150 and platelets down from 100 to 80.This is as per expectation since the cells from my nodes are now in my blood stream and BTKi impacts bone marrow (platelets)
Sizes of my nodes has shrunk significantly
Uric acid on target.
I have to watch out for bruising or bleeding.
So far so good.No changes in diet or lifestyle.
Name of game is stay positive!