Caris Life Sciences molecular cancer profiling

beebe, I had the profiling of my tumor done (not by Caris). They note the genetic mutations of your tumor. They match your mutations to any chemotherapeutic agent that has been used against that mutation. You end up with a list of chemotherapy drugs that have been used successfully, used unsuccessfully and those that are being tested in clinical trials. All three chemotherapeutic drug that were pressed upon me had already been tested against my mutations and had failed to affect the mutation. At University of Pittsburg they refused to treat me without a port for one agent, oral and injectible drugs for two others without somatic testing. I was surprised to find that it wasn't a choice I would be allowed to make. I found a proton center that would treat with chemo. And had successful treatment without useless chemotherapeutic side effects.
There may be no chemo information on some of your mutations. The data base has enlarged enormously in the seven years since my somatic testing. I think this testing is crucial to your experience as a cancer patient. I suggest that you accept all testing available. Best wishes

beebe, I had the profiling of my tumor done (not by Caris). They note the genetic mutations of your tumor. They match your mutations to any chemotherapeutic agent that has been used against that mutation. You end up with a list of chemotherapy drugs that have been used successfully, used unsuccessfully and those that are being tested in clinical trials. All three chemotherapeutic drug that were pressed upon me had already been tested against my mutations and had failed to affect the mutation. At University of Pittsburg they refused to treat me without a port for one agent, oral and injectible drugs for two others without somatic testing. I was surprised to find that it wasn't a choice I would be allowed to make. I found a proton center that would treat with chemo. And had successful treatment without useless chemotherapeutic side effects.
There may be no chemo information on some of your mutations. The data base has enlarged enormously in the seven years since my somatic testing. I think this testing is crucial to your experience as a cancer patient. I suggest that you accept all testing available. Best wishes

I was diagnosed bile duct cancer and had liver resection at Montefiore in Pittsburgh in Sept. 2024
Now snowbird but having bad side effects from chemo pills so now they want me to try Gemcitabine IV UGH!!

Foundation 1 did my testing.