Did anyone undergo Car-T therapy for B cell lymphoma?

I am 11 months in as well tiredness has long past for me. Did a lot of exercise to help me get past that.

My son received CAR T Cell Transplant 11 mo ago.
He is still cancer free. He is well, but gets very tired.
Does anyone else have this problem? Barb

@kevin_153, here are a few additional resources should you be interested in researching a bit more about CAR-T trials at Mayo Clinic or a potential second opinion:

- Clinical trials at Mayo Clinic search, https://www.mayo.edu/research/clinical-trials
- If you are interested in inquiring about a potential second opinion at Mayo Clinic, http://mayocl.in/1mtmR63
- Mayo Clinic's CAR-T cell therapy homepage, https://www.mayoclinic.org/departments-centers/car-t-cell-therapy-program/home/orc-20404317

@kevin_153, you mentioned that you relapsed from your stem cell transplant within 10 months. Many members have inquired about the process of undergoing a stem cell transplant, even though you relapsed, are you comfortable sharing your overall experience with your autologous stem cell transplant?

Easier said than done actually, @dazlin. Google returns few clear, plain language answers regarding the definitions of "reactive and predominant lymphoid nodules". Here's an extensive article from Science Direct on
- Lymph nodes https://www.sciencedirect.com/topics/neuroscience/lymph-node

Additionally I found the following:
"Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a type of lymphoma that develops from abnormal B lymphocytes (B cells, which are a type of white blood cell). NLPHL is not very common – around 1 in 20 cases (5%) of Hodgkin lymphoma are NLPHL."
In this case predominant means that lymphocytes are the predominant cell type.

What Are Reactive Lymph Nodes? https://www.healthline.com/health/reactive-lymph-node

I'd be interested in hearing how your hematologist explains these terms to you. Please let us know.

@ann...not a big deal.
I didn't mean for anyone to go out of guidelines. Was simply a vocabulary definition...which I could easily Google...no concerns. Wishing you and your husband the very best! Have a great day!

Really wish we could help, but it is not wise to be "practicing medicine without a license" on a forum like this. LOL! We are wishing you the best and hope you find a medical professional to answer your question soon.

Oh, sure...not a problem. I asked because I read a post here about a patient with Predominant. Thanks!

Sorry--We would love to be able to help you, but this is a patient support group. We are not licensed medical professionals, and therefore are not qualified to answer your question. (And even if some of us may know the answer, we should not answer it on this forum.) Your question should be answered by a physician, specifically a hematologist/oncologist. If you are being treated for a lymphoma, you can ask your own hematologist/oncologist. Or perhaps Lisa, our moderator, can direct you to a Mayo Clinic medical professional who is qualified to answer your question.

Can anyone explain the difference between Reactive and Predominant lymphoid nodules?

I hadn't thought about a second opinion from Mayo until now. I did get a second opinion from the UCHealth University of Colorado Hospital. They didn't have the Allogene Car-T trial. They wanted me to go through radiation and then to a bone marrow transplant with a donor.